Maleki Masoud, Yousefi Mahdi, Bazzaz Sayyed Mojtaba Mousavi, Tabassi Sayyed Abolghasem Sajadi, Rakhshandeh Hasan, Hamedi Shokouh Sadat, Haghighi Gholamreza
M.D., Dermatologist, Professor, Cutaneous Leishmaniasis Research Center, Department of Dermatology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
M.D., Ph.D., Assistant Professor, Department of Persian Medicine, Faculty of Persian and Complementary Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Electron Physician. 2017 Nov 25;9(11):5854-5862. doi: 10.19082/5854. eCollection 2017 Nov.
Cutaneous Leishmaniasis (CL) which is prevalent in all continents and is classified by the WHO as one of the neglected tropical diseases, existed in the past also, and discovered ancient works confirm this issue. The lack of adaptation of diseases between Persian Medicine (PM) and Modern medicine, led to no usage of effective therapeutic experiences of prior physicians.
The purpose of this study is finding skin lesions adapted to CL in PM for usage of same disease treatment in the next clinical trials, and the use of approved therapies in CL.
In a narrative review, without time limitation, documentary study was conducted for different names and clinical aspects of CL in printed and electronic resources of modern medicine such as: Rook's Textbook of Dermatology, Harper's Textbook of Pediatric Dermatology, PubMed, and Embase. Then, found names were searched in printed and electronic resources of PM such as: Al-Qanun fi al-tibb, Al-Tasrif leman ajeza an-e-Taliff, JamiTib 1.5 published by Noorsoft.org. Then, skin lesions which were similar to CL with these aspects were searched: clinical manifestation and forms, chronicity, curability, mosquito bite, were studied in references of PM. Finally, matching, syllogism and logical inference were performed and conclusion was made.
Forty-five names for CL were found in the searched resources. However, only Balkhieh, Kheyroonieh and Baghdadi button were names found in PM resources. Also, from 61 studied skin lesions in PM resources, only 6 cases had similarities to CL.
In spite of the existence of CL's similarity with Balkhieh, Kheyroonieh and the Baghdadi button, there are serious differentiations. Zat-ol-asl rashes and reddish solb rashes, kinds of stranger rashes, probably adapted with CL.
皮肤利什曼病（CL）在各大洲均有流行，世界卫生组织将其列为被忽视的热带病之一，过去就已存在，古代文献证实了这一问题。波斯医学（PM）与现代医学对疾病的适应性不足，导致先前医生的有效治疗经验未被采用。
本研究的目的是在波斯医学中找到与皮肤利什曼病相适应的皮肤病变，以便在未来的临床试验中用于相同疾病的治疗，并采用皮肤利什曼病的批准疗法。
在一项无时间限制的叙述性综述中，对现代医学的印刷和电子资源（如：《鲁克皮肤病学教科书》《哈珀儿科皮肤病学教科书》、PubMed和Embase）中皮肤利什曼病的不同名称和临床方面进行了文献研究。然后，在波斯医学的印刷和电子资源（如：《医典》《医学集成》、Noorsoft.org出版的Jami Tib 1.5）中搜索找到的名称。然后，在波斯医学参考文献中搜索与皮肤利什曼病在这些方面相似的皮肤病变：临床表现和形式、慢性、可治愈性、蚊虫叮咬。最后，进行匹配、三段论和逻辑推理并得出结论。
在所搜索的资源中发现了45个皮肤利什曼病的名称。然而，在波斯医学资源中仅发现了巴尔基耶、凯鲁尼耶赫和巴格达迪纽扣这几个名称。此外，在波斯医学资源中研究的61种皮肤病变中，只有6例与皮肤利什曼病有相似之处。
尽管皮肤利什曼病与巴尔基耶、凯鲁尼耶赫和巴格达迪纽扣存在相似性，但仍有严重差异。扎特-奥拉斯皮疹和微红的索尔布皮疹，即各种奇特皮疹，可能与皮肤利什曼病相适应。
