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雾化利多卡因作为反应性气道功能障碍综合征的替代疗法

Nebulized Lidocaine as an Alternative Therapy for Reactive Airway Dysfunction Syndrome.

作者信息

Özyiğit Leyla Pur, Erer Ayşen, Okumuş Gülfer, Çağatay Tülin, Kıyan Esen, Erkan Feyza

机构信息

Department of Allergy and Immunology, Koç University Faculty of Medicine, İstanbul, Turkey.

Department of Chest Diseases, İstanbul University Faculty of Medicine, İstanbul, Turkey.

出版信息

Turk Thorac J. 2016 Apr;17(2):82-83. doi: 10.5578/ttj.17.2.017. Epub 2016 Apr 1.

Abstract

Reactive airway dysfunction syndrome (RADS) is a variant of irritant-induced asthma that develops in subjects without prior bronchoobstructive disease, following high-level exposure to nonimmunogenic irritants. Recommended maintenance treatment for RADS is not different from asthma. But in some cases, severe symptoms may persist despite the bronchodilators and corticosteroids. We describe the first case of a patient with RADS, unresponsive to all medical agents, who was successfully treated with lidocaine.

摘要

反应性气道功能障碍综合征(RADS)是刺激性诱发哮喘的一种变体,发生于无既往支气管阻塞性疾病的个体,在高浓度接触非免疫原性刺激物之后。RADS推荐的维持治疗与哮喘并无不同。但在某些情况下,尽管使用了支气管扩张剂和皮质类固醇,严重症状仍可能持续。我们描述了首例RADS患者,对所有药物均无反应,而利多卡因成功治愈了该患者。

相似文献

10
Irritant-induced asthma.刺激性哮喘。
Curr Opin Allergy Clin Immunol. 2012 Apr;12(2):140-4. doi: 10.1097/ACI.0b013e32835143b8.

本文引用的文献

1
EAACI position paper: irritant-induced asthma.欧洲变应原学会立场文件:刺激性诱导哮喘。
Allergy. 2014 Sep;69(9):1141-53. doi: 10.1111/all.12448. Epub 2014 Jul 5.

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