钙通道阻滞剂过量的潜在有害影响及当前可用的处理方法。
The potential detrimental effects of calcium channel blockers' overdose and current available management.
作者信息
Agarwal Manyoo A, Flatt David, Khouzam Rami N
机构信息
Department of Internal Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
Division of Cardiovascular Diseases, Department of Internal Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
出版信息
Ann Transl Med. 2018 Jan;6(1):16. doi: 10.21037/atm.2018.01.03.
Abstract
Calcium channel blockers (CCBs) are prescribed in a wide variety of cardiovascular conditions. Overdose of this commonly used drug can result in negative physiologic consequences including severe hypotension and even death due to metabolic and hemodynamic compromise. We report the fatal case of an amlodipine overdose, which caused intractable acidosis and cardiovascular failure in a 51-year-old male.
摘要
钙通道阻滞剂（CCBs）被广泛用于治疗各种心血管疾病。过量服用这种常用药物会导致负面的生理后果，包括严重低血压，甚至因代谢和血流动力学受损而死亡。我们报告了一例氨氯地平过量致死的病例，该病例导致一名51岁男性出现顽固性酸中毒和心血管衰竭。
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