儿童抗生素耐药性日益加剧的威胁。
The Growing Threat of Antibiotic Resistance in Children.
机构信息
Department of Pediatrics, Rush Medical College, Rush University Medical Center, 1710 W. Harrison Street, Suite 710 POB, Chicago, IL 60612, USA.
Department of Pediatrics, Rush Medical College, Rush University Medical Center, 1710 W. Harrison Street, Suite 710 POB, Chicago, IL 60612, USA.
出版信息
Infect Dis Clin North Am. 2018 Mar;32(1):1-17. doi: 10.1016/j.idc.2017.11.001.
Abstract
Antimicrobial resistance is a global public health threat and a danger that continues to escalate. These menacing bacteria are having an impact on all populations; however, until recently, the increasing trend in drug-resistant infections in infants and children has gone relatively unrecognized. This article highlights the current clinical and molecular data regarding infection with antibiotic-resistant bacteria in children, with an emphasis on transmissible resistance and spread via horizontal gene transfer.
摘要
抗微生物药物耐药性是一个全球性的公共卫生威胁，而且这种威胁还在不断加剧。这些危险的细菌对所有人群都有影响；然而，直到最近，婴儿和儿童中耐药性感染的上升趋势才开始受到关注。本文重点介绍了目前关于儿童感染抗生素耐药细菌的临床和分子数据，特别强调了可传播的耐药性和通过水平基因转移的传播。
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