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医用大麻合法化是否能减少与止痛药相关的成瘾和死亡?

Do medical marijuana laws reduce addictions and deaths related to pain killers?

机构信息

RAND, Santa Monica, United States.

RAND, Santa Monica, United States; NBER Cambridge, MA, United States.

出版信息

J Health Econ. 2018 Mar;58:29-42. doi: 10.1016/j.jhealeco.2017.12.007. Epub 2018 Feb 3.

Abstract

Recent work finds that medical marijuana laws reduce the daily doses filled for opioid analgesics among Medicare Part-D and Medicaid enrollees, as well as population-wide opioid overdose deaths. We replicate the result for opioid overdose deaths and explore the potential mechanism. The key feature of a medical marijuana law that facilitates a reduction in overdose death rates is a relatively liberal allowance for dispensaries. As states have become more stringent in their regulation of dispensaries, the protective value generally has fallen. These findings suggest that broader access to medical marijuana facilitates substitution of marijuana for powerful and addictive opioids.

摘要

最近的研究发现,医用大麻合法化降低了医疗保险处方药部分和医疗补助计划参保者的阿片类镇痛药日剂量,也降低了全民范围内的阿片类药物过量死亡人数。我们复制了阿片类药物过量死亡人数的结果,并探讨了潜在的机制。促进过量死亡率降低的医用大麻合法化的关键特征是对药房的相对宽松的规定。随着各州对药房的监管越来越严格,这种保护作用通常会下降。这些发现表明,更广泛地获得医用大麻有助于用大麻替代强效且易上瘾的阿片类药物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4b5/7867411/86478420dd7b/nihms-939452-f0001.jpg

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