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直接转送至具备经皮冠状动脉介入治疗能力的医院对院外心脏骤停患者出院存活率的影响。

Impact of the direct transfer to percutaneous coronary intervention-capable hospitals on survival to hospital discharge for patients with out-of-hospital cardiac arrest.

机构信息

Université de Montréal, Montréal, Québec, Canada; Hôpital du Sacré-Cœur de Montréal, Montréal, Québec, Canada; Institut de Cardiologie de Montréal, Montréal, Québec, Canada.

Université de Montréal, Montréal, Québec, Canada; Hôpital du Sacré-Cœur de Montréal, Montréal, Québec, Canada.

出版信息

Resuscitation. 2018 Apr;125:28-33. doi: 10.1016/j.resuscitation.2018.01.048. Epub 2018 Feb 2.

Abstract

AIMS

Patients suffering from out-of-hospital cardiac arrest (OHCA) are frequently transported to the closest hospital. Percutaneous coronary intervention (PCI) is often indicated following OHCA. This study's primary objective was to determine the association between being transported to a PCI-capable hospital and survival to discharge for patients with OHCA. The additional delay to hospital arrival which could offset a potential increase in survival associated with being transported to a PCI-capable center was also evaluated.

METHODS

This study used a registry of OHCA in Montreal, Canada. Adult patients transported to a hospital following a non-traumatic OHCA were included. Hospitals were dichotomized based on whether PCI was available on-site or not. The effect of hospital type on survival to discharge was assessed using a multivariable logistic regression. The added prehospital delay which could offset the increase in survival associated with being transported to a PCI-capable center was calculated using that regression.

RESULTS

A total of 4922 patients were included, of whom 2389 (48%) were transported to a PCI-capable hospital and 2533 (52%) to a non-PCI-capable hospital. There was an association between being transported to a PCI-capable center and survival to discharge (adjusted odds ratio = 1.60 [95% confidence interval 1.25-2.05], p < .001). Increasing the delay from call to hospital arrival by 14.0 min would offset the potential benefit of being transported to a PCI-capable center.

CONCLUSIONS

It could be advantageous to redirect patients suffering from OHCA patients to PCI-capable centers if the resulting expected delay is of less than 14 min.

摘要

目的

患有院外心脏骤停(OHCA)的患者经常被送往最近的医院。OHCA 后常需要进行经皮冠状动脉介入治疗(PCI)。本研究的主要目的是确定将患者送往 PCI 能力医院与 OHCA 患者出院存活率之间的关联。还评估了到达医院的额外延迟,这可能会抵消与送往 PCI 能力中心相关的潜在生存增加。

方法

本研究使用了加拿大蒙特利尔的 OHCA 登记处。纳入了在非创伤性 OHCA 后被送往医院的成年患者。根据是否现场提供 PCI,将医院分为两类。使用多变量逻辑回归评估医院类型对出院存活率的影响。使用该回归计算可能抵消与送往 PCI 能力中心相关的生存增加的院前额外延迟。

结果

共纳入 4922 例患者,其中 2389 例(48%)被送往 PCI 能力医院,2533 例(52%)被送往非 PCI 能力医院。与送往 PCI 能力中心相关的出院存活率存在关联(调整后的优势比=1.60 [95%置信区间 1.25-2.05],p<0.001)。将从呼叫到到达医院的时间延迟增加 14.0 分钟,将抵消送往 PCI 能力中心的潜在益处。

结论

如果预期的延迟少于 14 分钟,将 OHCA 患者重新定向送往 PCI 能力中心可能是有利的。

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