Nassif Daniel V, Pereira João S
Department of Neurology, Pedro Ernesto University Hospital, State University of Rio de Janeiro, Rio de Janeiro, Brazil.
Psychogeriatrics. 2018 Mar;18(2):143-150. doi: 10.1111/psyg.12302. Epub 2018 Feb 6.
Parkinson's disease (PD) is a progressive neurological disorder characterized by a large number of motor and non-motor features. Fatigue is one of the most common and most disabling symptoms among patients with PD, and it has a significant impact on their quality of life. Although fatigue has been recognized for a long time, its pathophysiology remains poorly understood, and there is no evidence to support any therapeutic approach in PD patients. Expert consensus on case definition and diagnostic criteria for PD-related fatigue have been recently published, and although they still need to be adequately validated, they provide a great step forward in the study of fatigue. The goal of this article is to provide relevant information for the identification and management of patients with fatigue.
帕金森病（PD）是一种进行性神经疾病，具有大量运动和非运动特征。疲劳是帕金森病患者中最常见且最致残的症状之一，对他们的生活质量有重大影响。尽管疲劳早已被认识到，但其病理生理学仍知之甚少，且尚无证据支持针对帕金森病患者的任何治疗方法。最近已发表了关于帕金森病相关疲劳的病例定义和诊断标准的专家共识，尽管仍需充分验证，但它们在疲劳研究方面向前迈出了一大步。本文的目的是为疲劳患者的识别和管理提供相关信息。
