Ghanbarzadeh L, Saraei M, Kia E B, Amini F, Sharifdini M
Department of Medical Parasitology and Mycology,School of Medicine,Qazvin University of Medical Sciences,Qazvin,Iran.
Department of Medical Parasitology and Mycology,School of Public Health,Tehran University of Medical Sciences,Tehran,Iran.
J Helminthol. 2019 Mar;93(2):149-153. doi: 10.1017/S0022149X17001225. Epub 2018 Feb 7.
Trichostrongylus spp. are primarily parasites of ruminants, but humans can become infected as accidental hosts. Information about the clinical aspects of human trichostrongyliasis is limited. This study investigated the clinical and haematological characteristics of a large number of trichostrongyliasis patients. In the Fouman district of Guilan Province in northern Iran, during 2015-2016, 60 patients were identified as positive for Trichostrongylus spp., using stool examination methods. The clinical manifestations and demographic data of all patients were recorded and further analysed. Twenty-three patients (38.3%) were male and 37 (61.7%) were female. Among the individuals infected only with Trichostrongylus, only nine patients (16.4%) were asymptomatic. Forty-six patients (83.6%) presented with gastrointestinal (76.3%), pulmonary (30.9%) and cutaneous (12.7%) symptoms. No statistically significant relationship was found between clinical manifestations and sex or age groups. Ten patients (18.1%) revealed eosinophilia and five (9.1%) presented with hypochromic microcytic anaemia. The relationship between eosinophilia and age group, sex and clinical manifestations showed no statistical significance. Our study indicated that trichostrongyliasis may be a major parasitic aetiology for gastrointestinal symptoms and eosinophilia in rural residents of endemic areas.
毛圆线虫属主要是反刍动物的寄生虫，但人类可作为偶然宿主被感染。关于人类毛圆线虫病临床方面的信息有限。本研究调查了大量毛圆线虫病患者的临床和血液学特征。在伊朗北部吉兰省的福曼地区，2015 - 2016年期间，采用粪便检查方法确定60例患者毛圆线虫属检测呈阳性。记录并进一步分析了所有患者的临床表现和人口统计学数据。23例患者（38.3%）为男性，37例（61.7%）为女性。在仅感染毛圆线虫的个体中，只有9例患者（16.4%）无症状。46例患者（83.6%）出现胃肠道症状（76.3%）、肺部症状（30.9%）和皮肤症状（12.7%）。未发现临床表现与性别或年龄组之间存在统计学显著关系。10例患者（18.1%）出现嗜酸性粒细胞增多，5例（9.1%）出现低色素小细胞性贫血。嗜酸性粒细胞增多与年龄组、性别和临床表现之间的关系无统计学意义。我们的研究表明，毛圆线虫病可能是流行地区农村居民胃肠道症状和嗜酸性粒细胞增多的主要寄生虫病因。
