Foodborne,Waterborne,Vectorborne,and Zoonotic Disease Section,Minnesota Department of Health,St. Paul,Minnesota,USA.
Epidemiol Infect. 2018 Mar;146(4):423-429. doi: 10.1017/S0950268818000079. Epub 2018 Feb 7.
Incubation period for non-typhoidal Salmonella (NTS) infections is generally reported as 6-72 h despite numerous reports of foodborne NTS outbreaks with median incubation periods >3 days. We summarised 16 years of Minnesota foodborne NTS outbreaks to better estimate the expected range of incubation periods for NTS infections. Of the 1517 NTS outbreak cases, 725 had enough data to calculate a precise incubation period. The median incubation period was 45 h; 77 (11%) cases had incubations ⩽12 h and 211 (29%) cases had incubations >72 h. Incubation period length varied by outbreak vehicle type, Salmonella serotype and outbreak setting. Based on our data, a more accurate description would be that the incubation of NTS infection is usually from 12 to 96 h, that incubations in >96 to 144 h (>4 to 6-day) range are not unusual and that incubations from 7 to 9 days and occasionally longer also occur.
非伤寒型沙门氏菌(NTS)感染的潜伏期通常报告为 6-72 小时,尽管有许多食源性 NTS 暴发的报告潜伏期中位数超过 3 天。我们总结了明尼苏达州 16 年来的食源性 NTS 暴发情况,以更好地估计 NTS 感染的预期潜伏期范围。在 1517 例 NTS 暴发病例中,725 例有足够的数据来计算精确的潜伏期。潜伏期中位数为 45 小时;77 例(11%)潜伏期 ⩽12 小时,211 例(29%)潜伏期 >72 小时。潜伏期长度因暴发载体类型、沙门氏菌血清型和暴发环境而异。根据我们的数据,更准确的描述应该是,NTS 感染的潜伏期通常为 12-96 小时,潜伏期 >96-144 小时(>4-6 天)并不罕见,潜伏期为 7-9 天甚至更长时间也会发生。