Epidemic Intelligence Service, Epidemiology Workforce Branch, Division of Scientific Education and Professional Development, Centers for Disease Control and Prevention, Atlanta, Georgia.
Enteric Diseases Epidemiology Branch, Division of Foodborne, Waterborne and Environmental Diseases, National Center for Emerging Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.
Foodborne Pathog Dis. 2020 Feb;17(2):151-155. doi: 10.1089/fpd.2019.2641. Epub 2019 Sep 30.
Most nontyphoidal (NTS) illnesses in the United States are thought to be foodborne. However, transmission routes likely vary among the different serotypes. We developed a relative ranking of NTS serotypes according to the strength of their association with foodborne transmission. We used Laboratory-based Enteric Disease Surveillance data to estimate the proportion of infections for each serotype reported from 1998 to 2015 and Foodborne Disease Outbreak Surveillance System data to calculate the proportion of foodborne outbreak-associated illnesses caused by each serotype. We calculated the ratios of these proportions to create a foodborne relatedness (FBR) measure for each serotype. Of the top 20 serotypes, Saintpaul (2.14), Heidelberg (1.61), and Berta (1.48) had the highest FBR measures; Mississippi (0.01), Bareilly (0.13), and Paratyphi B variant L(+) tartrate(+) (0.20) had the lowest. The FBRs for the three most prevalent serotypes were 1.22 for Enteritidis, 0.77 for Typhimurium, and 1.16 for Newport. This method provides a quantitative approach to estimating the relative differences in the likelihood that an illness caused by a particular serotype was transmitted by food, which may aid in tailoring strategies to prevent illnesses and guide future research into serotype-specific source attribution.
大多数在美国发生的非伤寒型（NTS）疾病被认为是食源性的。然而，不同血清型的传播途径可能有所不同。我们根据 NTS 血清型与食源性传播的关联强度，对其进行了相对排名。我们使用基于实验室的肠道疾病监测数据来估计从 1998 年到 2015 年报告的每一种血清型感染的比例，以及食源性疾病爆发监测系统数据来计算每一种血清型引起的食源性爆发相关疾病的比例。我们计算了这些比例的比值，为每一种血清型创建了一个食源性相关性（FBR）度量。在排名前 20 的血清型中，圣保罗（2.14）、海德堡（1.61）和贝尔塔（1.48）的 FBR 最高；密西西比（0.01）、巴雷利（0.13）和 Paratyphi B 变体 L(+) 酒石酸盐（+）（0.20）的 FBR 最低。三种最常见血清型的 FBR 分别为肠炎沙门氏菌 1.22、鼠伤寒沙门氏菌 0.77 和纽波特沙门氏菌 1.16。该方法提供了一种定量估计特定血清型引起的疾病通过食物传播的可能性相对差异的方法，这可能有助于制定预防疾病的策略，并指导针对血清型特异性源归因的未来研究。
