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新生儿皮质听觉诱发电位阈值的自动估计

Automated cortical auditory evoked potentials threshold estimation in neonates.

作者信息

Oliveira Lilian Sanches, Didoné Dayane Domeneghini, Durante Alessandra Spada

机构信息

Faculdade de Ciências Médicas da Santa Casa de São Paulo, Escola de Fonoaudiologia e Audiologia, São Paulo, SP, Brazil.

Universidade Federal do Rio Grande do Sul, Programa de Pós-graduação em Saúde da Criança e do Adolescente, Rio Grande do Sul, RS, Brazil.

出版信息

Braz J Otorhinolaryngol. 2019 Mar-Apr;85(2):206-212. doi: 10.1016/j.bjorl.2018.01.001. Epub 2018 Feb 2.

Abstract

INTRODUCTION

The evaluation of cortical auditory evoked potential has been the focus of scientific studies in infants. Some authors have reported that automated response detection is effective in exploring these potentials in infants, but few have reported their efficacy in the search for thresholds.

OBJECTIVE

To analyze the latency, amplitude and thresholds of cortical auditory evoked potential using an automatic response detection device in a neonatal population.

METHODS

This is a cross-sectional, observational study. Cortical auditory evoked potentials were recorded in response to pure-tone stimuli of the frequencies 500, 1000, 2000 and 4000Hz presented in an intensity range between 0 and 80dB HL using a single channel recording. P1 was performed in an exclusively automated fashion, using Hotelling's T statistical test. The latency and amplitude were obtained manually by three examiners. The study comprised 39 neonates up to 28 days old of both sexes with presence of otoacoustic emissions and no risk factors for hearing loss.

RESULTS

With the protocol used, cortical auditory evoked potential responses were detected in all subjects at high intensity and thresholds. The mean thresholds were 24.8±10.4dB NA, 25±9.0dB NA, 28±7.8dB NA and 29.4±6.6dB HL for 500, 1000, 2000 and 4000Hz, respectively.

CONCLUSION

Reliable responses were obtained in the assessment of cortical auditory potentials in the neonates assessed with a device for automatic response detection.

摘要

引言

皮层听觉诱发电位的评估一直是婴儿科学研究的重点。一些作者报告称,自动反应检测在探索婴儿的这些电位方面是有效的,但很少有人报告其在寻找阈值方面的功效。

目的

使用自动反应检测设备分析新生儿群体中皮层听觉诱发电位的潜伏期、波幅和阈值。

方法

这是一项横断面观察性研究。使用单通道记录,记录对频率为500、1000、2000和4000Hz的纯音刺激的皮层听觉诱发电位,刺激强度范围为0至80dB HL。P1采用完全自动化方式进行,使用霍特林T统计检验。潜伏期和波幅由三名检查者手动获取。该研究包括39名年龄在28天以内的新生儿,男女均有,耳声发射正常且无听力损失风险因素。

结果

按照所使用的方案,在所有受试者中均在高强度和阈值下检测到皮层听觉诱发电位反应。500、1000、2000和4000Hz的平均阈值分别为24.8±10.4dB NA、25±9.0dB NA、28±7.8dB NA和29.4±6.6dB HL。

结论

使用自动反应检测设备对新生儿进行皮层听觉电位评估时获得了可靠的反应。

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