Remy L
Biol Cell. 1986;56(2):97-105. doi: 10.1111/j.1768-322x.1986.tb00446.x.
Ultrastructurally, the intracellular lumen appears as a more or less spherical cavity with osmiophilic substance, bordered with microvilli and surrounded by a filamentous network. Epithelial cancer cells, both healthy cultured and hormonally stimulated in vivo, often present such structures, which probably result from a dysfunction of the Golgi apparatus and cytoskeleton. This characterizes an abortive secretory process, which may be the consequence of a great hormonal sensitivity of the cells or of a loss of differentiation criteria when they are cancerous or isolated for culture.
在超微结构上，细胞内腔呈现为一个或多或少呈球形的腔，腔内含有嗜锇性物质，腔的边缘有微绒毛，并被丝状网络包围。无论是健康培养的上皮癌细胞还是体内受到激素刺激的上皮癌细胞，常常呈现出这样的结构，这可能是高尔基体和细胞骨架功能障碍的结果。这表征了一个失败的分泌过程，这可能是细胞对激素高度敏感的结果，或者是当细胞癌变或为培养而分离时失去分化标准的结果。
