Division of Gastroenterology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Section of Gastroenterology, Hepatology, and Nutrition, University of Chicago Medical Center, Chicago, IL, USA.
Aliment Pharmacol Ther. 2018 Apr;47(7):913-921. doi: 10.1111/apt.14551. Epub 2018 Feb 7.
Despite advances in treatment, patients with inflammatory bowel disease (IBD) frequently require emergency department (ED) visits and hospitalisations.
To analyse trends in ED visits and subsequent hospitalisations for IBD in the United States (US).
Data were analysed from the Nationwide Emergency Department Sample (NEDS) years 2006-2014. The NEDS is the largest all-payer ED database in the US, weighted to represent 135 million visits/year. IBD was identified using ICD-9 codes for Crohn's disease (CD) or ulcerative colitis (UC). Surgeries were identified using procedure codes.
The frequency of IBD-ED visits increased 51.8%, from 90 846 visits in 2006 to 137 946 in 2014, which was statistically significant in linear regression. For comparison, all-case ED use between 2006 and 2014 increased 14.8%. In-patient hospitalisations from the ED decreased 12.1% for IBD (from 64.7% rate of hospitalisation from the ED in 2006 to 52.6% in 2014), with a UC:CD ratio of 1.2:1 in 2006 and 1.3:1 in 2014. Chi-square analysis revealed that this was a significant decrease. Surgery rates also showed a statistically significant decrease. The mean ED charge per patient rose 102.5% and the aggregate national cost of IBD-ED visits increased 207.5%. CD accounted for over twice as many visits as UC in both years. UC, age, male gender, highest income quartile, private insurance, Medicaid/Medicare, and tobacco use were associated with in-patient admissions.
The number of ED visits due to IBD and associated charges have continued to rise, while the rates of in-patient hospitalisations referred from the ED and surgeries have decreased.
尽管治疗取得了进展,但炎症性肠病(IBD)患者仍经常需要到急诊部(ED)就诊和住院。
分析美国(US)IBD 患者 ED 就诊和随后住院的趋势。
分析了 2006 年至 2014 年全国急诊部样本(NEDS)的数据。NEDS 是美国最大的所有付费 ED 数据库,经过加权以代表每年 1.35 亿次就诊。使用 ICD-9 编码为克罗恩病(CD)或溃疡性结肠炎(UC)识别 IBD。手术使用手术编码识别。
IBD-ED 就诊的频率增加了 51.8%,从 2006 年的 90846 次增加到 2014 年的 137946 次,线性回归分析显示这具有统计学意义。相比之下,2006 年至 2014 年间所有病例的 ED 使用量增加了 14.8%。ED 住院的 IBD 住院率下降了 12.1%(从 2006 年 ED 住院率的 64.7%降至 2014 年的 52.6%),2006 年 UC:CD 比值为 1.2:1,2014 年为 1.3:1。卡方分析显示这是显著下降。手术率也呈统计学显著下降。每位患者的 ED 收费平均增长了 102.5%,IBD-ED 就诊的全国总费用增长了 207.5%。在这两年中,CD 就诊的次数是 UC 的两倍多。UC、年龄、男性、收入最高的四分位数、私人保险、医疗补助/医疗保险和吸烟与住院有关。
由于 IBD 导致的 ED 就诊次数和相关费用持续增加,而从 ED 转介的住院率和手术率则有所下降。