观察性研究发现，即使是新生儿重症监护病房中光线的微小变化也能唤醒极早产儿。

Observational study found that even small variations in light can wake up very preterm infants in a neonatal intensive care unit.

机构信息

Laboratoire de Neurosciences Cognitives et Adaptatives, UMR 7364 CNRS/Université de Strasbourg, Strasbourg, France.

Médecine et Réanimation du nouveau-né, Service de Pédiatrie 2, Pôle Médico-Chirurgical Pédiatrique, Hôpital de Hautepierre, Centre Hospitalier Universitaire de Strasbourg, Strasbourg, France.

出版信息

Acta Paediatr. 2018 Jul;107(7):1191-1197. doi: 10.1111/apa.14261. Epub 2018 Feb 27.

DOI:10.1111/apa.14261

PMID:29412484

Abstract

AIM

This prospective observational study evaluated the behavioural responses of very preterm infants to spontaneous light variations.

METHODS

We measured spontaneous light variations in the incubators of 27 very preterm infants, with a median gestational age of 28 weeks (range 26-31 weeks), over 10 hours. All of them had been admitted to the neonatal care unit of the Strasbourg University Hospital, France, between April 2008 and July 2009. Two independent raters examined changes in the infants' behavioural states using video recordings. The percentage of awakenings was recorded when there were light variations and during control periods with no changes.

RESULTS

We analysed 275 periods following light variations and 275 control periods. The overall percentage of awakenings was greater during periods following a change in light than during control periods (16.3% vs 11%, p = 0.03). The extent of light protection affected the percentage of awakenings. In mild light protection, there were more awakenings following changes in light than in control periods (25.6% vs 6.7%, p = 0.01). This difference was not found in high light protection.

CONCLUSION

Very preterm infants can be woken up by small variations in light, when the light protection in their incubator is insufficient.

摘要

目的

本前瞻性观察研究评估了极早产儿对自然光变化的行为反应。

方法

我们测量了法国斯特拉斯堡大学医院新生儿重症监护病房 27 名胎龄中位数为 28 周（范围 26-31 周）的极早产儿在 10 小时内保育箱内自然光的自发变化。所有婴儿均于 2008 年 4 月至 2009 年 7 月入住。两名独立的评估员通过视频记录观察婴儿行为状态的变化。当自然光发生变化和控制期内没有变化时，记录婴儿觉醒的百分比。

结果

我们分析了 275 个自然光变化后和 275 个对照周期。与对照周期相比，自然光变化后婴儿觉醒的总体百分比更高（16.3%对 11%，p = 0.03）。光保护程度影响觉醒百分比。在轻度光保护下，自然光变化后婴儿的觉醒次数多于对照周期（25.6%对 6.7%，p = 0.01）。在高光保护下则没有发现这种差异。