The phospholipid contents in rat liver Golgi-rich membrane fractions after streptozotocin and/or prostaglandin treatment.

After dmPGE2 treatment, both alone or together with streptozotocin, the lower, statistically significant total PL contents (in mumoles P per mg of protein) in rat liver Golgi-rich membrane fractions were found. In these groups of investigated rats, the percentage of PE+PA were statistically significantly lower than in control. For the present it is impossible to certify, if there is a causal-result dependence between these two facts. The administration of streptozotocin alone (both after 6 or 11 days) caused the increase of PE+PA percentage, however not statistically significant.