环丙沙星治疗男性尿道淋病。
Ciprofloxacin for treating urethral gonorrhoea in men.
作者信息
Shahmanesh M, Shukla S R, Phillips I, Westwood A, Thin R N
出版信息
Genitourin Med. 1986 Apr;62(2):86-7. doi: 10.1136/sti.62.2.86.
Abstract
The effectiveness of a single oral dose of ciprofloxacin in eradicating urethral gonorrhoea was assessed in 18 men who received 250 mg and 26 men who were given 100 mg. All patients, including two infected with beta lactamase (penicillinase) producing strains of Neisseria gonorrhoeae (PPNG), were cured. The drug had no effect on infection with Chlamydia trachomatis or on the incidence of post gonococcal urethritis. Ciprofloxacin may be useful in patients hypersensitive to penicillins and cephalosporins, and the drug may also be useful in urethral gonorrhoea caused by PPNG strains.
摘要
对18名服用250毫克环丙沙星的男性和26名服用100毫克环丙沙星的男性进行了评估，以确定单次口服环丙沙星根除尿道淋病的有效性。所有患者，包括两名感染了产生β-内酰胺酶（青霉素酶）的淋病奈瑟菌菌株（PPNG）的患者，均被治愈。该药物对沙眼衣原体感染或淋菌性尿道炎的发病率没有影响。环丙沙星可能对青霉素和头孢菌素过敏的患者有用，该药物也可能对由PPNG菌株引起的尿道淋病有用。
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本文引用的文献
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2
Pharmacokinetics of ciprofloxacin after oral and intravenous administration in healthy volunteers.环丙沙星在健康志愿者口服和静脉给药后的药代动力学。
Eur J Clin Microbiol. 1984 Aug;3(4):355-9. doi: 10.1007/BF01977494.
3
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