Milgrom P, Fiset L
Int Dent J. 1986 Jun;36(2):71-6.
This paper has three parts: local anaesthetic adverse effects, haemorrhage control and altered immune response. Primary emphasis is placed on the problems with anaesthetics since their use is widespread. Every day, nearly 2 million injections of local anaesthetic are given in dental practice. From 2.5 to 10 per cent of patients experience adverse reactions. This adverse effect rate is 10 times higher than that in medicine for the same drugs. Allergic, toxic, idiosyncratic and psychogenic effects are discussed. New data on the role of local anaesthetic agents, vasoconstrictors and preservatives is presented. In addition, the problem of anaesthetic failure (occurring in over 10 per cent of patients) is explained. Treatment (drug and psychological) for anaesthetic related emergencies such as panic attacks, shortness of breath, palpitations and nausea is recommended. Prevention and treatment of haemorrhage is explained. Medical and dental conditions may increase clotting time (e.g., systemic disease or local factors such as granulation tissue). Preventive strategies are outlined and laboratory tests discussed. Emphasis should be placed on the use of local anaesthetics with vasoconstrictors, haemostatic agents and pressure. The final aspect of the paper discussed new data on problems for dentists arising with patients who have altered immune function. In particular AIDS is discussed from the point of view of protection of the dentist and dental treatment for the patient.
局部麻醉的不良反应、出血控制和免疫反应改变。由于局部麻醉剂使用广泛,因此主要重点放在麻醉相关问题上。在牙科实践中,每天有近200万次局部麻醉注射。2.5%至10%的患者会出现不良反应。这种不良反应发生率比使用相同药物的医学领域高出10倍。文中讨论了过敏、毒性、特异质性和精神性效应。还介绍了局部麻醉剂、血管收缩剂和防腐剂作用的新数据。此外,还解释了麻醉失败问题(超过10%的患者会出现)。推荐了针对麻醉相关紧急情况(如惊恐发作、呼吸急促、心悸和恶心)的治疗方法(药物和心理治疗)。阐述了出血的预防和治疗。医学和牙科状况可能会延长凝血时间(如全身性疾病或局部因素,如肉芽组织)。概述了预防策略并讨论了实验室检查。应强调使用含血管收缩剂的局部麻醉剂、止血剂和压迫止血。本文的最后一部分讨论了免疫功能改变患者给牙医带来问题的新数据。特别是从保护牙医和为患者进行牙科治疗的角度讨论了艾滋病。