[以巨核细胞为主且伴有恶性巨核细胞增殖的急性髓系白血病。附3例报告]
[Acute myeloid leukemia with megakaryocytic predominance and malignant megakaryocyte proliferation. Apropos of 3 cases].
作者信息
Nigro M, Ascari E, Compagnoni A, Menestrina F
出版信息
Ann Anat Pathol (Paris). 1979;24(2):171-84.
Three cases of acute myeloid leukemia with megakaryocyte predominance are reported. In the first case megakaryocytosis was particularly evident in bone marrow, liver and spleen. In the second case high content of megakaryocytes was observed in the bone marrow and spleen, during the preleukemic phase only. Third case exhibited a strong predominance of megakaryocytes exclusively within the bone marrow. The characteristics of such observations and their nosologic position within myeloproliferative disorders group are discussed, with special reference to modern views concerning myeloid leukemia.
报告了3例以巨核细胞为主的急性髓系白血病。第一例中，巨核细胞增多在骨髓、肝脏和脾脏中尤为明显。第二例中，仅在白血病前期在骨髓和脾脏中观察到高含量的巨核细胞。第三例仅在骨髓内显示巨核细胞明显占优势。讨论了这些观察结果的特征及其在骨髓增殖性疾病组中的疾病分类位置，并特别提及了有关髓系白血病的现代观点。
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