Zhang Baokun, Liu Jingwen, Zhu Yi, Zhang Wei
Department of Orthopedic Surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, 600 Yishan Road, Shanghai, 200233, China.
Int Orthop. 2018 Aug;42(8):1949-1955. doi: 10.1007/s00264-018-3798-x. Epub 2018 Feb 8.
The treatment of vertical femoral neck fractures in young patients is a worldwide challenge. The purpose of this study is to introduce a new configuration of cannulated screw fixation in vertical femoral neck fractures by comparing with using ordinary cannulated compression screw (OCCS) alone biomechanically and clinically.
Biomechanically, 20 synthetic femur models of femoral neck fractures with 20° of VN angle were divided into two groups. The first group was fixed with three ordinary cannulated compression screws defined as OCCS group; the second group was fixed with two Headless Cannulated Compression Screws (HCCS) plus an OCCS, defined as combination group and tested for axial stiffness and load to failure. Clinically, a prospective study was designed with 59 patients who have vertical femoral neck fractures and were treated with cannulated screw, including 31 patients with three ordinary cannulated compression screws alone and 28 patients with an ordinary cannulated compression screw plus two headless cannulated compression screws.
Biomechanically, our results showed that there was no significant difference of axial stiffness between OCCS group and combination group (109.92 ± 10.81 vs. 123.49 ± 15.13 N/mm, P = 0.145). But, the maximum load to failure of the combination group performed significant advantages than that of the OCCS group (446.85 ± 76.25 vs. 302.92 ± 80.46 N, P = 0.007). Clinically, the rates of fixation failure in the group treated with OCCS alone were 41.9%, while in the group treated with two types of screws were14.3% (P = 0.048).
Our results suggested that using new configuration of an OCCS plus two HCCSs improved the outcome of vertical femoral neck fractures (FNF) patients compared to those using OCCS alone, which provides a new choice for treatment of FNF.
年轻患者股骨颈垂直骨折的治疗是一项全球性挑战。本研究的目的是通过与单独使用普通空心加压螺钉(OCCS)进行生物力学和临床比较,介绍一种用于股骨颈垂直骨折的新型空心螺钉固定构型。
在生物力学方面,将20个具有20°垂直颈干角的合成股骨颈骨折模型分为两组。第一组用3枚普通空心加压螺钉固定,定义为OCCS组;第二组用2枚无头空心加压螺钉(HCCS)加1枚OCCS固定,定义为联合组,并测试轴向刚度和破坏载荷。在临床方面,设计了一项前瞻性研究,纳入59例接受空心螺钉治疗的股骨颈垂直骨折患者,其中31例仅使用3枚普通空心加压螺钉,28例使用1枚普通空心加压螺钉加2枚无头空心加压螺钉。
生物力学方面,结果显示OCCS组和联合组之间的轴向刚度无显著差异(109.92±10.81 vs. 123.49±15.13 N/mm,P = 0.145)。但是,联合组的最大破坏载荷比OCCS组具有显著优势(446.85±76.25 vs. 302.92±80.46 N,P = 0.007)。临床方面,单独使用OCCS治疗组的固定失败率为41.9%,而使用两种螺钉治疗组的固定失败率为14.3%(P = 0.048)。
我们的结果表明,与单独使用OCCS相比,使用OCCS加2枚HCCS的新构型改善了股骨颈垂直骨折(FNF)患者的治疗效果,为FNF的治疗提供了一种新选择。