Liang H
Zhonghua Zhong Liu Za Zhi. 1986 Jan;8(1):29-31.
Cytotoxic effect of HPD plus light irradiation on PTK2 and HeLa cells in vitro were studied by laser microbeam irradiation. The dynamic changes, in three different steps as observed in the cells ranged from visible damage to cell lysis, were recorded at the monocellular level. It was found that the speed of the cytotoxic process varied chiefly with the dose of light used. The cytotoxic progress of PTK2 and HeLa cells was compared and analyzed. In addition, the cytotoxic effects of three different laser wavelengths (6328A, 5145A and 4880A) plus HPD were compared. The most significant killing effect occurred at 6328A wavelength of red light.
通过激光微束照射研究了血卟啉衍生物（HPD）加光照对体外培养的PTK2细胞和HeLa细胞的细胞毒性作用。在单细胞水平记录了细胞中观察到的从可见损伤到细胞裂解的三个不同阶段的动态变化。发现细胞毒性过程的速度主要随所用光剂量而变化。对PTK2细胞和HeLa细胞的细胞毒性进程进行了比较和分析。此外，还比较了三种不同激光波长（6328埃、5145埃和4880埃）加HPD的细胞毒性作用。在6328埃红光波长处出现了最显著的杀伤效果。
