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[冠状动脉内镜的首次临床经验]

[First clinical experience with coronary endoscopy].

作者信息

Hombach V, Höher M, Hannekum A, Hügel W, Buran B, Höpp H W, Hirche H

出版信息

Dtsch Med Wochenschr. 1986 Jul 25;111(30):1135-40. doi: 10.1055/s-2008-1068597.

Abstract

In four different groups coronary endoscopy and endoscopy of peripheral vessels was carried out, using two ultrathin fibre endoscopes with a working length of 120 cm and a diameter of 1.4 or 1.8 mm. In a first series of seven cadaver hearts, normal vessels were found in three, one had high-grade stenosis and in the remaining three there were flat whitish atheromatous changes, rather scar-like in appearance. In a second series of 16 patients, the vascular wall in the iliac region was easily visualised in ten, while six showed diffuse atherosclerotic changes of the wall. In a third group of eight patients, coronary endoscopy was carried out at the time of balloon-catheter dilatation; endoscopy was successful in five patients. In two of them, the stenosis or occlusion to be dilated by balloon was visualised. In a fourth series, good visualisation of the vessels was obtained intraoperatively in seven out of nine patients, and in addition the course of the vessel distal to the stenosis as well as the site of anastomosis with the venous bypass graft could be seen. No serious side-effects of the procedure have yet been observed. Coronary endoscopy opens up a new dimension in the morphological assessment of coronary vascular changes. The method must, however, still be regarded as experimental.

摘要

使用两台工作长度为120厘米、直径为1.4或1.8毫米的超细纤维内窥镜,对四个不同的组进行了冠状动脉内窥镜检查和外周血管内窥镜检查。在第一组七具尸体心脏中,三具发现血管正常,一具存在高度狭窄,其余三具存在扁平的白色动脉粥样硬化改变,外观类似瘢痕。在第二组16例患者中,十例患者髂区血管壁易于观察,六例显示血管壁弥漫性动脉粥样硬化改变。在第三组八例患者中,在球囊导管扩张时进行冠状动脉内窥镜检查;五例患者检查成功。其中两例患者中,可观察到拟用球囊扩张的狭窄或闭塞情况。在第四组中,九例患者中有七例在术中实现了血管的良好观察,此外还能看到狭窄远端血管的走行以及与静脉旁路移植物的吻合部位。尚未观察到该操作的严重副作用。冠状动脉内窥镜检查为冠状动脉血管变化的形态学评估开辟了一个新的维度。然而,该方法仍应被视为实验性的。

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