Wu Jing, Kuang Li, Fu Lijuan
Shanghai Jiao Tong University School of Nursing, Shanghai, People's Republic of China.
Department of Cardiothoracic Surgery, Shanghai Children's Medical Center Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Congenit Heart Dis. 2018 Mar;13(2):194-202. doi: 10.1111/chd.12586. Epub 2018 Feb 8.
The aim of this study was to evaluate the effects of inspiratory muscle training (IMT) in chronic heart failure (CHF) patients.
We searched MEDLINE, EMBASE, Cochrane Library, CINHAL, and CBMdisc to collect controlled trials on the application of inspiratory muscle training in CHF patients from the establishment of these databases to November 2016. Two reviewers independently screened literature according to the inclusion and exclusion criteria, extracted data, and assessed the quality of literature. Meta-analysis was conducted by software RevMan5.3.
Eight studies involving 302 patients were identified. Meta-analysis indicated that IMT significantly improved PI , V /VCO slope and dyspnea (weighted mean difference [WMD] = 16.52, 95% CI: 13.87-19.17, P < .01; WMD = -5.78, 95% CI: -7.72 to -3.85, P < .01; SMD = -0.95, 95% CI: -1.5 to -0.39, P < .01), and descriptive results showed that long-term IMT (≥6 weeks) can improve the quality of life of CHF patients, and patients in IMT group also have a significant improvement in 6-minute walking distance test (6-MWD).
IMT can improve pulmonary function, exercise tolerance, and quality of life of CHF patients and relieve the symptom of dyspnea.
本研究旨在评估吸气肌训练（IMT）对慢性心力衰竭（CHF）患者的影响。
我们检索了MEDLINE、EMBASE、Cochrane图书馆、CINHAL和CBMdisc，以收集从这些数据库建立至2016年11月期间关于吸气肌训练在CHF患者中应用的对照试验。两名研究者根据纳入和排除标准独立筛选文献、提取数据并评估文献质量。采用RevMan5.3软件进行荟萃分析。
共纳入8项研究，涉及302例患者。荟萃分析表明，IMT显著改善了吸气峰压（PI）、每分通气量与二氧化碳排出量比值（V /VCO）斜率和呼吸困难（加权均数差[WMD]=16.52，95%可信区间[CI]：13.87 - 19.17，P <.01；WMD = -5.78，95%CI：-7.72至-3.85，P <.01；标准化均数差[SMD]= -0.95，95%CI：-1.5至-0.39，P <.01），描述性结果显示长期IMT（≥6周）可改善CHF患者的生活质量，且IMT组患者在6分钟步行距离测试（6-MWD）中也有显著改善。
IMT可改善CHF患者的肺功能、运动耐量和生活质量，并缓解呼吸困难症状。
