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验证蒙特利尔认知评估基础版在埃及老年神经认知障碍患者样本中的应用。

Validation of Montreal Cognitive Assessment-Basic in a sample of elderly Egyptians with neurocognitive disorders.

机构信息

a Department of Psychiatry, Faculty of Medicine , Cairo University , Cairo , Egypt.

b Department of Family Medicine, Faculty of Medicine , Cairo University , Cairo , Egypt.

出版信息

Aging Ment Health. 2019 May;23(5):551-557. doi: 10.1080/13607863.2018.1428936. Epub 2018 Feb 9.

DOI:10.1080/13607863.2018.1428936
PMID:29424560
Abstract

BACKGROUND AND OBJECTIVES

Montreal Cognitive Assessment-Basic (MoCA-B) is a modified version of the MoCA that is especially suitable for use in elderly subjects with low education. The Authors translated the tool into Arabic and they aimed at validation of this tool in a sample of elderly Egyptians.

METHODS

The study included 93 patients, 60 years and older, fulfilling the DSM-5 criteria of Mild Neurocognitive Disorder (NCD) (39 patients) and Major Neurocognitive Disorder (54 patients) that were compared to 112 community dwelling elder subjects. All subjects were assessed using the MoCA-B, Mini-Mental State Examination (MMSE), and the Clinical Dementia Rating Scale (CDR) in addition to the required laboratory and radiological investigations.

RESULTS

MoCA-B demonstrated good internal consistency (Cronbach's alpha = 0.915) and content validity in discrimination between normal and diseased subjects. It showed superior sensitivity and specificity when compared to MMSE in screening for Mild NCD (AUC MoCA-B = 0.988 versus MMSE = 0.939). The recommended cut-off was 21/22 with sensitivity of 92.5% and specificity of 98.2% for detecting Mild NCD and 16/17 with sensitivity of 90.7% and specificity of 97.4% for detecting Major NCD (dementia).

CONCLUSION

The Arabic MoCA-B is a valid cognitive assessment tool in elderly Egyptian subjects.

摘要

背景与目的

蒙特利尔认知评估-基础版(MoCA-B)是 MoCA 的一种改良版本,特别适用于受教育程度较低的老年受试者。作者将该工具翻译成阿拉伯语,并旨在对埃及老年人群体进行验证。

方法

本研究纳入了 93 名年龄在 60 岁及以上、符合 DSM-5 轻度认知障碍(NCD)标准(39 名患者)和重度认知障碍(54 名患者)的患者,并与 112 名居住在社区的老年受试者进行了比较。所有受试者均接受了 MoCA-B、简易精神状态检查(MMSE)和临床痴呆评定量表(CDR)的评估,此外还进行了必要的实验室和影像学检查。

结果

MoCA-B 表现出良好的内部一致性(Cronbach's alpha = 0.915)和区分正常和患病受试者的内容效度。与 MMSE 相比,MoCA-B 在筛查轻度 NCD 时具有更高的敏感性和特异性(AUC MoCA-B = 0.988 与 MMSE = 0.939)。建议的截断值为 21/22,对轻度 NCD 的敏感性为 92.5%,特异性为 98.2%,对重度 NCD(痴呆)的敏感性为 90.7%,特异性为 97.4%。

结论

阿拉伯语版 MoCA-B 是一种适用于埃及老年人群体的有效的认知评估工具。

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