Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-0146.
J Biol Chem. 2018 Mar 30;293(13):4603-4605. doi: 10.1074/jbc.TM118.002255. Epub 2018 Feb 7.
This 11th Thematic Metals in Biology Thematic Series deals with copper, a transition metal with a prominent role in biochemistry. Copper is a very versatile element, and both deficiencies and excesses can be problematic. The five Minireviews in this series deal with several aspects of copper homeostasis in microorganisms and mammals and the role of this metal in two enzymes, copper-only superoxide dismutase and cytochrome oxidase.
本第 11 期《生物学主题系列:金属》专题探讨了过渡金属铜在生物化学中的重要作用。铜是一种用途广泛的元素,其缺乏和过量都会带来问题。本系列的五篇综述文章分别探讨了微生物和哺乳动物中铜稳态的几个方面,以及该金属在两种酶(铜只有超氧化物歧化酶和细胞色素氧化酶)中的作用。