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马肠道寄生虫病的新视角:监测蠕虫感染的见解

New Perspectives in Equine Intestinal Parasitic Disease: Insights in Monitoring Helminth Infections.

作者信息

Pfister Kurt, van Doorn Deborah

机构信息

Parasite Consulting GmbH, Wendschatzstrasse 8, CH-3006 Berne, Switzerland; Institute of Comp. Tropical Medicine and Parasitology, LMU - University Munich, Munich, Germany.

Department of Infectious Diseases and Immunology, Faculty of Vet. Medicine, Utrecht University, Yalelaan 1, 3584CL Utrecht, The Netherlands.

出版信息

Vet Clin North Am Equine Pract. 2018 Apr;34(1):141-153. doi: 10.1016/j.cveq.2017.11.009. Epub 2018 Feb 6.

Abstract

Regular anthelmintic treatment has contributed to anthelmintic resistance in horse helminths. This mass anthelmintic treatment was originally developed owing to a lack of larvicidal drugs against Strongylus vulgaris. The high prevalence of anthelmintic resistance and shortening of strongyle egg reappearance period after avermectins/moxidectins requires epidemiologically appropriate and sustainable measures. Selective anthelmintic treatment is a much-needed deworming approach: More than 50% of adult horses manifest no strongyle egg excretion. In this article, selective anthelmintic treatment procedure is described, with the specific focus on the advantages of an evidence-based, medically appropriate, and sustainable treatment system that slows the development of anthelmintic resistance.

摘要

常规驱虫治疗导致了马体内蠕虫产生抗药性。这种大规模驱虫治疗最初是由于缺乏针对普通圆线虫的杀幼虫药物而开展的。抗药性的高流行率以及使用阿维菌素/莫西菌素后圆线虫虫卵再出现期的缩短,需要采取符合流行病学且可持续的措施。选择性驱虫治疗是一种急需的驱虫方法:超过50%的成年马没有排出圆线虫虫卵。本文描述了选择性驱虫治疗程序,特别关注基于证据、医学上恰当且可持续的治疗系统的优势,该系统可减缓抗药性的发展。

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