墨西哥登革热病毒1型（DENV-1）的基因型变异性分析揭示了一种新的墨西哥谱系的存在。
Genotypic variability analysis of DENV-1 in Mexico reveals the presence of a novel Mexican lineage.
作者信息
González-Durán Elizabeth, Vázquez-Pichardo Mauricio, Torres-Flores Jesús Miguel, Garcés-Ayala Fabiola, Méndez-Tenorio Alfonso, Curiel-Quesada Everardo, Ortiz-Alcántara Joanna María, Castelán-Sánchez Hugo Gildardo, Salas-Benito Juan Santiago, Torres-Longoria Belem, López-Martínez Irma, Hernández-Rivas Lucía, Membrillo-Hernández Jorge, Díaz-Quiñonez José Alberto, Ramírez-González José Ernesto
机构信息
Instituto de Diagnóstico y Referencia Epidemiológicos "Dr. Manuel Martínez Báez" (InDRE), Secretaría de Salud, Francisco de P. Miranda 177, Lomas de Plateros, 01480, Mexico, CDMX, Mexico.
Escuela Nacional de Ciencias Biológicas (ENCB), Instituto Politécnico Nacional, 11340, Mexico, CDMX, Mexico.
出版信息
Arch Virol. 2018 Jun;163(6):1643-1647. doi: 10.1007/s00705-018-3759-0. Epub 2018 Feb 9.
Here, we report for the first time the circulation of dengue virus type 1 (DENV-1) belonging to the lineage IV of genotype V (African American genotype) based on phylogenetic analysis of nucleotide sequences from 10 DENV-1-positive samples obtained in Mexico between 2012 and 2014. Our data revealed that the lineages III and IV of DENV-1 genotype V were found circulating during the same period, probably explaining the rise in the number of cases of severe dengue during that period.
在此，我们首次报告，基于对2012年至2014年间在墨西哥获得的10份登革热病毒1型（DENV-1）阳性样本的核苷酸序列进行系统发育分析，发现属于基因型V（非裔美国人基因型）谱系IV的DENV-1在传播。我们的数据显示，DENV-1基因型V的谱系III和IV在同一时期被发现正在传播，这可能解释了该时期严重登革热病例数的增加。
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