Vegter M W
Faculty of Science, Institute for Science in Society, Radboud University Nijmegen, P.O. Box 9010, 6500 GL, Nijmegen, The Netherlands.
Med Health Care Philos. 2018 Dec;21(4):443-456. doi: 10.1007/s11019-018-9828-z.
Precision Medicine has become a common label for data-intensive and patient-driven biomedical research. Its intended future is reflected in endeavours such as the Precision Medicine Initiative in the USA. This article addresses the question whether it is possible to discern a new 'medical cosmology' in Precision Medicine, a concept that was developed by Nicholas Jewson to describe comprehensive transformations involving various dimensions of biomedical knowledge and practice, such as vocabularies, the roles of patients and physicians and the conceptualisation of disease. Subsequently, I will elaborate my assessment of the features of Precision Medicine with the help of Michel Foucault, by exploring how precision medicine involves a transformation along three axes: the axis of biomedical knowledge, of biomedical power and of the patient as a self. Patients are encouraged to become the managers of their own health status, while the medical domain is reframed as a data-sharing community, characterised by changing power relationships between providers and patients, producers and consumers. While the emerging Precision Medicine cosmology may surpass existing knowledge frameworks; it obscures previous traditions and reduces research-subjects to mere data. This in turn, means that the individual is both subjected to the neoliberal demand to share personal information, and at the same time has acquired the positive 'right' to become a member of the data-sharing community. The subject has to constantly negotiate the meaning of his or her data, which can either enable self-expression, or function as a commanding Superego.
精准医学已成为数据密集型和患者驱动型生物医学研究的一个通用标签。其预期的未来体现在美国精准医学计划等努力中。本文探讨了是否有可能在精准医学中辨别出一种新的“医学宇宙观”,这一概念由尼古拉斯·朱森提出,用于描述涉及生物医学知识和实践各个维度的全面变革,如词汇表、患者和医生的角色以及疾病的概念化。随后,我将借助米歇尔·福柯阐述我对精准医学特征的评估,探讨精准医学如何沿着三个轴进行变革:生物医学知识轴、生物医学权力轴和患者作为自我的轴。鼓励患者成为自身健康状况的管理者,而医学领域则被重新构建为一个数据共享社区,其特点是提供者与患者、生产者与消费者之间的权力关系不断变化。虽然新兴的精准医学宇宙观可能超越现有的知识框架;但它掩盖了先前的传统,并将研究对象简化为单纯的数据。这反过来意味着,个体既受到新自由主义要求分享个人信息的影响,同时又获得了成为数据共享社区成员的积极“权利”。主体必须不断协商其数据的意义,这些数据既可以实现自我表达,也可以充当命令式的超我。