Institute for History of Medicine and Science Studies, University of Lübeck.
Ber Wiss. 2022 Sep;45(3):373-383. doi: 10.1002/bewi.202200020.
In the introduction to his Spalt und Fuge, Hans-Jörg Rheinberger points to the possibility that we are currently experiencing a new turning point regarding forms of experimentation, which is characterized by the growing importance of high-throughput methods and big data analytics. This essay will explore the thesis that data-intensive research indeed constitutes a form of post-experimental research by interrogating research practices in precision medicine. Section 1 will introduce this thesis and highlight salient features of precision medicine as an example of post-experimental research. Section 2 suggests approach as a category that is broader than experimental system, as discussed by Rheinberger, and can serve to analyze and compare diverse forms of research, including experimental and post-experimental practices. The essay concludes with a reflection on how categories developed for the historiography of recent science might require an update when the science or its context changes (section 3).
在他的《分裂与缝隙》（Spalt und Fuge）的引言中，汉斯-约尔格·莱茵贝格（Hans-Jörg Rheinberger）指出，我们目前可能正在经历一种新的实验形式的转折点，其特点是高通量方法和大数据分析的重要性日益增加。本文将通过探讨精准医学中的研究实践来探讨数据密集型研究确实构成了一种后实验研究的论点。第 1 节将介绍这一论点，并将精准医学作为后实验研究的一个例子来强调其显著特征。第 2 节提出，方法作为一个范畴比莱茵贝格所讨论的实验系统更为广泛，可以用来分析和比较不同形式的研究，包括实验和后实验实践。本文最后反思了当科学或其背景发生变化时，为近代科学史发展起来的范畴可能需要更新（第 3 节）。
