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[感染LAV/HTLV III病毒患者的间质性淋巴细胞性肺炎和多腺病]

[Interstitial lymphoid pneumonia and polyadenopathies in patients infected with the LAV/HTLV III virus].

作者信息

Couderc L J, Hervé P, Solal-Celigny P, Herman D, D'Agay M F, Morinet F, Matheron S, Rabian C, Caubarrere I, Clauvel J P

出版信息

Presse Med. 1986 Jun 14;15(24):1127-30.

PMID:2942907
Abstract

Seven patients of Haitian and Central African origin were investigated for interstitial pneumonitis and unexplained chronic lymphadenopathy. A study of broncho-alveolar lavage fluid showed no opportunistic micro-organisms and disclosed a high alveolar lymphocyte count with more than 80% T8+ cells. In 3 patients, open lung biopsy showed lymphoid interstitial pneumonitis. Follicular hyperplasia was a constant finding in lymph nodes. Benign lymphocytic infiltration was found in other organs of all patients, associated with polyclonal hyperimmunoglobulinaemia, low peripheral T4+ cell count and LAV-Ig G antibodies.

摘要

对7名海地和中非裔患者进行了间质性肺炎和不明原因慢性淋巴结病的调查。支气管肺泡灌洗液体研究显示没有机会性微生物,并发现肺泡淋巴细胞计数高,T8 +细胞超过80%。3名患者的开胸肺活检显示淋巴样间质性肺炎。滤泡增生是淋巴结中的常见表现。在所有患者的其他器官中均发现良性淋巴细胞浸润,伴有多克隆高免疫球蛋白血症、外周血T4 +细胞计数低和LAV-Ig G抗体。

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