Lin Qiong-Xi, Wu Gui-Hua, Zhang Ling, Wang Zeng-Jian, Pan Ning, Xu Cai-Juan, Jing Jin, Jin Yu
Faculty of Maternal and Child Health, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.
Zhongguo Dang Dai Er Ke Za Zhi. 2018 Feb;20(2):134-139. doi: 10.7499/j.issn.1008-8830.2018.02.011.
To explore the recognition ability and abnormal processing characteristics to basic emotional faces in the early phase in children with autism spectrum disorders (ASD).
Photos of Chinese static faces with four basic emotions (fearful, happy, angry and sad) were used as stimulus. Twenty-five ASD children and twenty-two age- and gender-matched typical developed children (normal controls) were asked to match the emotional faces with words. Event-related potential (ERP) data were recorded concurrently.
N170 latencies for total emotion and fearful face in the left temporal region were faster than in the right one in normal controls (P<0.05), but the results were not noted in ASD children. Further, N170 latencies in the left temporal region of ASD children were slower than normal controls for total emotion, fearful and happy faces (P<0.05), and their N170 latencies in the right temporal region were prone to slower than normal controls for angry and fearful faces.
The holistic perception speed of emotional faces in the early cognitive processing phase in ASD children is slower than normal controls. The lateralized response in the early phase of recognizing emotional faces may be aberrant in children with ASD.
探讨孤独症谱系障碍（ASD）儿童早期对基本情绪面孔的识别能力及异常加工特征。
以具有四种基本情绪（恐惧、高兴、愤怒和悲伤）的中国静态面孔照片作为刺激物。25名ASD儿童和22名年龄及性别匹配的发育正常儿童（正常对照组）被要求将情绪面孔与词语进行匹配。同时记录事件相关电位（ERP）数据。
正常对照组中，左侧颞区总情绪和恐惧面孔的N170潜伏期比右侧快（P<0.05），但ASD儿童未出现此结果。此外，ASD儿童左侧颞区总情绪、恐惧和高兴面孔的N170潜伏期比正常对照组慢（P<0.05），其右侧颞区愤怒和恐惧面孔的N170潜伏期倾向于比正常对照组慢。
ASD儿童在早期认知加工阶段对情绪面孔的整体感知速度比正常对照组慢。ASD儿童在识别情绪面孔早期阶段的侧化反应可能异常。
