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通过周围性面神经麻痹诊断的原发性中枢神经系统移植后淋巴组织增生性疾病

Primary Central Nervous System Post-transplant Lymphoproliferative Disorder Diagnosed by Peripheral Facial Nerve Palsy.

作者信息

Imafuku Aya, Tanaka Kiho, Marui Yuji, Ubara Yoshifumi, Takaichi Kenmei, Tomikawa Shinji, Ota Yasunori, Fujii Takeshi, Ishii Yasuo

机构信息

Department of Nephrology Center, Toranomon Hospital, Japan.

Department of Pathology, Toranomon Hospital, Japan.

出版信息

Intern Med. 2018 Jul 1;57(13):1899-1903. doi: 10.2169/internalmedicine.9613-17. Epub 2018 Feb 9.

DOI:10.2169/internalmedicine.9613-17
PMID:29434151
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6064700/
Abstract

Although primary central nervous system post-transplant lymphoproliferative disorder (PCNS-PTLD) causes various symptoms depending on the tumor region, there has been no previous report of PCNS-PTLD in the cerebellopontine angle that was diagnosed due to peripheral facial nerve palsy. We herein report a case involving a 62-year-old man with PCNS-PTLD in the cerebellopontine angle who was diagnosed due to peripheral facial nerve palsy. The reduction of immunosuppressive therapy, whole-brain radiotherapy, intrathecal chemotherapy, and rituximab were effective in treating this patient. Physicians should therefore be mindful that PCNS-PTLD can cause peripheral facial nerve palsy in renal transplant recipients.

摘要

尽管原发性中枢神经系统移植后淋巴细胞增生性疾病（PCNS-PTLD）根据肿瘤部位会引发各种症状，但此前尚无因周围性面神经麻痹而诊断为小脑脑桥角PCNS-PTLD的报告。我们在此报告一例62岁男性小脑脑桥角PCNS-PTLD患者，其因周围性面神经麻痹而确诊。减少免疫抑制治疗、全脑放疗、鞘内化疗和利妥昔单抗对该患者治疗有效。因此，医生应注意PCNS-PTLD可导致肾移植受者出现周围性面神经麻痹。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de11/6064700/039c77e82e8b/1349-7235-57-1899-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de11/6064700/0548b9700df4/1349-7235-57-1899-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de11/6064700/43d9464189ad/1349-7235-57-1899-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de11/6064700/77e0a9043619/1349-7235-57-1899-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de11/6064700/039c77e82e8b/1349-7235-57-1899-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de11/6064700/0548b9700df4/1349-7235-57-1899-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de11/6064700/43d9464189ad/1349-7235-57-1899-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de11/6064700/77e0a9043619/1349-7235-57-1899-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de11/6064700/039c77e82e8b/1349-7235-57-1899-g004.jpg

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2
Post-transplant Lymphoproliferative Disorder: A Single-Center Experience.
Transplant Proc. 2015 May;47(4):981-4. doi: 10.1016/j.transproceed.2015.03.017.
3
Imaging the facial nerve: a contemporary review.面神经成像：当代综述
Radiol Res Pract. 2013;2013:248039. doi: 10.1155/2013/248039. Epub 2013 May 23.
异基因干细胞移植后原发性中枢神经系统移植后淋巴细胞增殖性疾病：一例报告
Front Oncol. 2024 Jan 19;14:1284577. doi: 10.3389/fonc.2024.1284577. eCollection 2024.
4
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5
Risk of de novo cancers after transplantation: results from a cohort of 7217 kidney transplant recipients, Italy 1997-2009.意大利 1997-2009 年 7217 例肾移植受者队列的新发癌症风险。
Eur J Cancer. 2013 Jan;49(2):336-44. doi: 10.1016/j.ejca.2012.09.013. Epub 2012 Oct 10.
6
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