Folks T M, Chused T M, Portnoy D, Edison L, Leiserson W, Sell K W
Cell Immunol. 1986 Jan;97(1):164-72. doi: 10.1016/0008-8749(86)90386-2.
Peripheral blood lymphocytes from adult and adolescent chimpanzees, as well as adult humans, were studied for phenotypic surface markers by flow cytometry. Lymphocytes from chimpanzees were found to have increased numbers of Leu-1-, Leu-2+ cells as compared to humans. These cells, following preparative electronic cell sorting, were shown to possess natural killer function. Further analysis of this subpopulation indicated that they lacked responsiveness to a number of T-cell mitogens. The differences in lymphocyte subpopulations between chimpanzees and humans can almost be totally accounted for by the Leu-1-, Leu-2+ cells. Phylogenetic disparity between these two species may also be found within this population.
通过流式细胞术对成年和青少年黑猩猩以及成年人类的外周血淋巴细胞进行了表型表面标志物研究。发现与人类相比，黑猩猩的淋巴细胞中Leu-1-、Leu-2+细胞数量增加。经制备性电子细胞分选后的这些细胞显示具有自然杀伤功能。对该亚群的进一步分析表明，它们对多种T细胞有丝分裂原无反应性。黑猩猩和人类淋巴细胞亚群之间的差异几乎完全由Leu-1-、Leu-2+细胞所导致。在这一细胞群体中也可能发现这两个物种之间的系统发育差异。
