Pawar Dushyant, Calara Anna, Jacob Roy, Beck Nancy, Peiris Alan N
School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX, USA.
Department of Radiology, University Medical Center, Lubbock, TX, USA.
Case Rep Gastrointest Med. 2017;2017:6432063. doi: 10.1155/2017/6432063. Epub 2017 Dec 25.
Constipation is a common condition. Hydrogen peroxide enemas have rarely been reported as a home remedy for constipation in the pediatric age group. We present a case report and literature review of hydrogen peroxide induced colitis in pediatric siblings, aged 2 years and 9 years. The siblings presented with vomiting and bloody diarrhea an hour following the enema. Physical exam, vital signs, blood, and electrolyte counts were normal, but CT scans showed mucosal thickening of the rectum and colon. Their symptoms resolved after oral intake was curtailed and fluids were replaced intravenously. We discuss existing reports of complications from hydrogen peroxide enemas. Patients may present with abdominal pain and bloody diarrhea. Onset of symptoms varied from minutes to a day and bowel ulceration with necrosis and perforation has occurred, although fatality is rare. Diagnostic tests included computed tomography (CT) scan, sigmoidoscopy, or biopsy. Recovery period ranged from 3 days to 8 months. Public education regarding the dangers of hydrogen peroxide enemas is needed.
便秘是一种常见病症。过氧化氢灌肠剂作为儿科年龄组便秘的家庭疗法鲜有报道。我们报告一例2岁和9岁儿科同胞兄弟姐妹因过氧化氢诱发结肠炎的病例，并进行文献综述。这对同胞兄弟姐妹在灌肠后一小时出现呕吐和血性腹泻。体格检查、生命体征、血液和电解质计数均正常，但CT扫描显示直肠和结肠黏膜增厚。在减少口服摄入并静脉补充液体后，他们的症状得到缓解。我们讨论了过氧化氢灌肠剂并发症的现有报告。患者可能出现腹痛和血性腹泻。症状发作时间从数分钟到一天不等，尽管死亡率很低，但已发生肠溃疡伴坏死和穿孔。诊断检查包括计算机断层扫描（CT）、乙状结肠镜检查或活检。恢复期从3天到8个月不等。需要对公众进行关于过氧化氢灌肠剂危险性的教育。
