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可卡因使用者中低剂量过氧化氢灌肠诱发的化学性结肠炎

Chemical Colitis Induced by Low-dose Hydrogen Peroxide Enema in a Cocaine User.

作者信息

Galo Jason, Zaydlin Michelle, Celli-Cabada Diego A

机构信息

Internal Medicine, University of Miami Miller School of Medicine/Jackson Memorial Hospital, Miami, USA.

Psychiatry, University of Miami Miller School of Medicine/Jackson Memorial Hospital, Miami, USA.

出版信息

Cureus. 2020 Feb 17;12(2):e7017. doi: 10.7759/cureus.7017.

DOI:10.7759/cureus.7017
PMID:32211253
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7081737/
Abstract

Home remedies are usually cheap options to alleviate conditions commonly used prior to patients seeking medical advice for their problems, and are sometimes the only option for some populations that have otherwise no healthcare access. Hydrogen peroxide enemas appear to be an easily accessible solution to constipation, with "how to guides" found ubiquitously on the Internet. To our knowledge there are a few case reports exposing its complications. Our case reports complications in a patient who used a lower than average dose of a hydrogen peroxide enema, albeit compounded by cocaine abuse. Our experience suggests that the risks of concurrent use of cocaine and hydrogen peroxide enemas can lead to dangerous vasoconstriction, decreased blood flood to the bowel mucosa, and might lead to significant complications to otherwise tolerable doses of corrosive agents.

摘要

家庭疗法通常是在患者就其问题寻求医疗建议之前用于缓解常见病症的廉价选择,有时对于那些无法获得医疗保健的人群来说是唯一的选择。过氧化氢灌肠剂似乎是一种易于获得的治疗便秘的方法,互联网上随处可见“使用指南”。据我们所知,有一些病例报告揭示了其并发症。我们的病例报告了一名使用低于平均剂量过氧化氢灌肠剂的患者出现的并发症,尽管该患者同时滥用可卡因。我们的经验表明,同时使用可卡因和过氧化氢灌肠剂的风险可能导致危险的血管收缩、肠道黏膜血流量减少,并可能使原本可耐受剂量的腐蚀性剂引发严重并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0e5/7081737/d6e7a33cbdd4/cureus-0012-00000007017-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0e5/7081737/d6e7a33cbdd4/cureus-0012-00000007017-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0e5/7081737/d6e7a33cbdd4/cureus-0012-00000007017-i01.jpg

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本文引用的文献

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Chemical colitis caused by hydrogen peroxide enema in a child: case report and literature review.过氧化氢灌肠致儿童化学性结肠炎:病例报告及文献复习
Environ Health Toxicol. 2018 Feb 27;33(1):e2018005. doi: 10.5620/eht.e2018005. eCollection 2018.
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Home Remedy Use Among African American and White Older Adults.非裔美国和白人老年人使用家庭疗法的情况。
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