Karimi Ramin, Sharma Ashish, Tran Kevin, Montgomery Sebastian
Coliseum Medical Center, Macon, GA.
HCA Healthc J Med. 2021 Apr 28;2(2):105-108. doi: 10.36518/2689-0216.1096. eCollection 2021.
Description Chemical colitis is defined as inflammation of the large intestine or colon as a result of exposure from a harsh chemical through an enema or other procedure. In this case, the chemical is hydrogen peroxide, which is commonly used as an antiseptic for minor abrasions. Hydrogen peroxide enemas were once popular for difficult to treat constipation. However, resultant colitis and proctitis limited its use. When administered rectally in a high enough concentration, intense abdominal pain and transient bloody diarrhea can occur, with the majority of affected patients making a full recovery with supportive management. Here we discuss a case of an accidental low concentration hydrogen peroxide enema in an otherwise healthy young adult that emphasized the dangers of hydrogen peroxide damage to mucosal membranes.
描述 化学性结肠炎被定义为由于通过灌肠或其他操作接触刺激性化学物质而导致的大肠或结肠炎症。在本病例中，该化学物质是过氧化氢，它通常用作治疗轻微擦伤的防腐剂。过氧化氢灌肠剂曾因用于治疗难治性便秘而流行。然而，由此导致的结肠炎和直肠炎限制了其使用。当以足够高的浓度经直肠给药时，可能会出现剧烈腹痛和短暂的血性腹泻，大多数受影响的患者通过支持性治疗可完全康复。在此，我们讨论一例原本健康的年轻成年人意外使用低浓度过氧化氢灌肠的病例，该病例强调了过氧化氢对黏膜造成损伤的危险性。
