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双胞胎中出现的亚急性皮肤型红斑狼疮。

Subacute cutaneous lupus erythematosus presenting in twins.

作者信息

Montuno Michael A, Church Ann A, Schoch Jennifer J, Andrews Israel D

机构信息

Department of Dermatology, College of Medicine, University of Florida, Gainesville, FL, USA.

Division of Pediatric Dermatology, Department of Dermatology, College of Medicine, University of Florida, Gainesville, FL, USA.

出版信息

Pediatr Dermatol. 2018 Mar;35(2):e128-e131. doi: 10.1111/pde.13434. Epub 2018 Feb 13.

Abstract

Subacute cutaneous lupus erythematosus is a clinically distinct form of cutaneous lupus erythematosus, with age of onset typically in the second to fifth decades. Eleven cases have been reported in childhood, and we present the first known case of subacute cutaneous lupus erythematosus in identical twins. Although flares are typically photo-induced, we present an annular eruption typical of subacute cutaneous lupus erythematosus with concurrent pinworm infestation, with recurrence of disease with cutaneous larva migrans. The patient's identical twin had a similar eruption with pinworm infection. This case highlights the possibility of parasitic infestation as a trigger for subacute cutaneous lupus erythematosus in genetically susceptible individuals.

摘要

亚急性皮肤型红斑狼疮是一种临床上有独特表现的皮肤型红斑狼疮,发病年龄通常在第二个至第五个十年。儿童期已报告11例,我们报告了同卵双胞胎中首例已知的亚急性皮肤型红斑狼疮病例。虽然皮疹发作通常由光照诱发,但我们展示了一例伴有蛲虫感染的典型亚急性皮肤型红斑狼疮环形皮疹,以及皮肤幼虫移行症导致的疾病复发。患者的同卵双胞胎有类似的伴有蛲虫感染的皮疹。该病例突出了在遗传易感性个体中,寄生虫感染作为亚急性皮肤型红斑狼疮触发因素的可能性。

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