Viennois Emilie, Chassaing Benoit
a Institute for Biomedical Sciences, Georgia State University , Atlanta , GA.
b Neuroscience Institute, Georgia State University , Atlanta , GA.
Gut Microbes. 2018 Feb 13;9(3):1-4. doi: 10.1080/19490976.2017.1421885.
The intestinal tract is inhabited by a large and diverse community of bacteria, collectively referred to as the gut microbiota. Composed of 500-1000 distinct species, the intestinal microbiota plays an important role in immunity and metabolism. However, alterations in its composition are associated with a variety of inflammatory diseases including obesity, diabetes, and inflammatory bowel disease (IBD). Among many other factors, our diet impacts microbiota composition and function, in either beneficial or detrimental ways. In this addendum, we will discuss our recent findings on how dietary emulsifying agents can directly and detrimentally impact the microbiota, leading to inflammatory diseases and cancer.
肠道中栖息着大量种类多样的细菌群落，统称为肠道微生物群。肠道微生物群由500 - 1000个不同的物种组成，在免疫和代谢中发挥着重要作用。然而，其组成的改变与多种炎症性疾病有关，包括肥胖、糖尿病和炎症性肠病（IBD）。在许多其他因素中，我们的饮食以有益或有害的方式影响微生物群的组成和功能。在本附录中，我们将讨论我们最近关于膳食乳化剂如何直接且有害地影响微生物群，从而导致炎症性疾病和癌症的研究发现。
