University of North Carolina Health Care, Chapel Hill, North Carolina; and
Divisions of Neonatology and.
Pediatrics. 2018 Mar;141(3). doi: 10.1542/peds.2017-1143. Epub 2018 Feb 8.
Neonatal hypoglycemia is a common problem, often requiring management in the NICU. Nonpharmacologic interventions, including early breastfeeding and skin-to-skin care (SSC), may prevent hypoglycemia and the need to escalate care. Our objective was to maintain mother-infant dyads in the mother-infant unit by decreasing hypoglycemia resulting in NICU transfer.
Inborn infants ≥35 weeks' gestation with at least 1 risk factor for hypoglycemia were included. Using quality-improvement methodology, a bundle for at-risk infants was implemented, which included a protocol change focusing on early SSC, early feeding, and obtaining a blood glucose measurement in asymptomatic infants at 90 minutes. The primary outcome was the overall transfer rate of at-risk infants to the NICU. Secondary outcomes were related to protocol adherence. Balancing measures, including the rate of symptomatic hypoglycemia and sepsis evaluations, were monitored. Statistical process control charts using standard interpretation rules were used to monitor for improvement in key aims.
For infants at risk for hypoglycemia, the NICU transfer rate decreased from 17% to 3% overall. Documented early feeding and SSC in at-risk newborns increased. The percent of at-risk infants transferred to the NICU who did not require intravenous dextrose decreased from 5% at baseline to 0.7% after intervention. There were no adverse outcomes observed in the period before or after the intervention.
The implementation of a quality-improvement intervention promoting SSC and early feeding in at-risk infants was associated with a decreased rate of transfer to the NICU for hypoglycemia.
新生儿低血糖是一种常见问题,通常需要在新生儿重症监护病房(NICU)进行管理。非药物干预措施,包括早期母乳喂养和皮肤接触(SSC),可能预防低血糖并减少需要升级治疗的情况。我们的目标是通过减少低血糖导致的 NICU 转院,使母婴在母婴病房中保持在一起。
纳入胎龄≥35 周且至少存在 1 种低血糖风险因素的新生儿。使用质量改进方法,为高危婴儿实施了一整套干预措施,包括改变协议,重点关注早期 SSC、早期喂养和在无症状婴儿出生 90 分钟时进行血糖测量。主要结局是高危婴儿整体转入 NICU 的转院率。次要结局与方案依从性相关。监测平衡措施,包括症状性低血糖和败血症评估的发生率。使用标准解释规则的统计过程控制图用于监测关键目标的改进情况。
对于有低血糖风险的婴儿,NICU 转院率从总体的 17%降至 3%。高危新生儿的早期喂养和 SSC 记录有所增加。未接受静脉葡萄糖治疗而转入 NICU 的高危婴儿比例从基线时的 5%降至干预后的 0.7%。在干预前后,没有观察到不良结局。
实施促进高危婴儿 SSC 和早期喂养的质量改进干预措施与低血糖转院至 NICU 的率降低相关。