Canadian Women's Heart Health Centre, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; Division of Cardiac Prevention and Rehabilitation, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
Canadian Women's Heart Health Centre, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; Division of Cardiac Prevention and Rehabilitation, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
Can J Cardiol. 2018 Apr;34(4):437-449. doi: 10.1016/j.cjca.2017.11.019. Epub 2017 Dec 5.
Cardiovascular disease (CVD) is the leading cause of death among Indigenous peoples in Canada. As rates of CVD rise, the impacts among the growing population of Indigenous women will emerge as an important health issue. The objective of this scoping review was to advance the state of knowledge about cardiovascular health research in Indigenous women in Canada. Five databases and grey literature (non-peer reviewed works) were searched to identify all studies that reported on the prevalence, pathophysiology, diagnosis, treatment, or interventions for CVD among adult Indigenous women in Canada, including First Nations, Métis, and Inuit. Searching identified 3194 potential articles; 61 of which were included. The most commonly researched topics were the prevalence of CVD, hypertension, and dyslipidemia. Rates of CVD and associated mortality among Indigenous women appear to have surpassed those of their nonindigenous counterparts. Very little research has examined the pathophysiology, diagnosis, and treatment of CVD. Gaps in the research identified the need for sex-based analyses, comparison with nonindigenous women, comprehensive longitudinal data, assessment of diagnosis criteria, development and evaluation of cardiovascular health interventions, and a better understanding of the role of culture and traditions in the prevention and treatment of CVD among Indigenous women. Although comprehensive CVD data are lacking, rates of CVD among Indigenous women in Canada are rising and are nearing or surpassing those of nonindigenous women. This review serves as a call to action to seek further research on the pathophysiology, diagnosis, and treatment of CVD among Indigenous women from across Canada.
心血管疾病（CVD）是加拿大原住民人群的主要死因。随着 CVD 发病率的上升，原住民妇女人口的增长将带来重要的健康问题。本研究旨在深入了解加拿大原住民妇女心血管健康研究的现状。通过检索五个数据库和灰色文献（未经同行评审的作品），确定了所有报告加拿大成年原住民妇女（包括第一民族、梅蒂斯和因纽特人）中 CVD 的流行率、病理生理学、诊断、治疗或干预措施的研究。检索共识别出 3194 篇潜在文章，其中 61 篇被纳入。研究最多的主题是 CVD、高血压和血脂异常的流行率。原住民妇女的 CVD 发病率和相关死亡率似乎已超过非原住民妇女。很少有研究检查 CVD 的病理生理学、诊断和治疗。研究中的差距表明需要进行基于性别的分析、与非原住民妇女进行比较、全面的纵向数据、评估诊断标准、制定和评估心血管健康干预措施，以及更好地了解文化和传统在预防和治疗原住民妇女 CVD 中的作用。尽管缺乏全面的 CVD 数据，但加拿大原住民妇女的 CVD 发病率正在上升，且接近或超过非原住民妇女。本综述呼吁在加拿大各地进一步研究原住民妇女的 CVD 病理生理学、诊断和治疗。
