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丹麦剖宫产的风险因素及医院间差异:一项队列研究。

Risk factors and between-hospital variation of caesarean section in Denmark: a cohort study.

作者信息

Wehberg Sonja, Guldberg Rikke, Gradel Kim Oren, Kesmodel Ulrik Schiøler, Munk Lis, Andersson Charlotte Brix, Jølving Line Riis, Nielsen Jan, Nørgård Bente Mertz

机构信息

Center for Clinical Epidemiology, Odense University Hospital, Odense, Denmark.

Research Unit of Clinical Epidemiology, Institute of Clinical Research, University of Southern Denmark, Odense, Denmark.

出版信息

BMJ Open. 2018 Feb 10;8(2):e019120. doi: 10.1136/bmjopen-2017-019120.

Abstract

OBJECTIVES

The aim of this study was to estimate the effects of risk factors on elective and emergency caesarean section (CS) and to estimate the between-hospital variation of risk-adjusted CS proportions.

DESIGN

Historical registry-based cohort study.

SETTINGS AND PARTICIPANTS

The study was based on all singleton deliveries in hospital units in Denmark from January 2009 to December 2012. A total of 226 612 births by 198 590 mothers in 29 maternity units were included.

PRIMARY AND SECONDARY OUTCOME MEASURES

We estimated (1) OR of elective and emergency CS adjusted for several risk factors, for example, body mass index, parity, age and size of maternity unit and (2) risk-adjusted proportions of elective and emergency CS to evaluate between-hospital variation.

RESULTS

The CS proportion was stable at 20%-21%, but showed wide variation between units, even in adjusted models. Large units performed significantly more elective CSs than smaller units, and the risk of emergency CS was significantly reduced compared with smaller units. Many of the included risk factors were found to influence the risk of CS. The most important risk factors were breech presentation and previous CS. Four units performed more CSs and one unit fewer CSs than expected.

CONCLUSION

The main risk factors for elective CS were breech presentation and previous CS; for emergency CS they were breech presentation and cephalopelvic disproportion. The proportions of CS were stable during the study period. We found variation in risk-adjusted CS between hospitals in Denmark. Although exhaustive models were applied, the results indicated the presence of systematic variation between hospital units, which was unexpected in a small, well-regulated country such as Denmark.

摘要

目的

本研究旨在评估风险因素对择期和急诊剖宫产(CS)的影响,并估计风险调整后的CS比例在不同医院之间的差异。

设计

基于历史登记的队列研究。

设置与参与者

该研究基于丹麦2009年1月至2012年12月期间医院单位的所有单胎分娩。纳入了29个产科单位中198590名母亲的226612例分娩。

主要和次要结局指标

我们估计了(1)针对多个风险因素(例如体重指数、产次、年龄和产科单位规模)调整后的择期和急诊CS的比值比(OR),以及(2)风险调整后的择期和急诊CS比例,以评估医院之间的差异。

结果

CS比例稳定在20% - 21%,但各单位之间存在很大差异,即使在调整模型中也是如此。大型单位进行的择期CS明显多于小型单位,与小型单位相比,急诊CS的风险显著降低。发现许多纳入的风险因素会影响CS的风险。最重要的风险因素是臀位和既往剖宫产史。有四个单位进行的CS比预期多,一个单位比预期少。

结论

择期CS的主要风险因素是臀位和既往剖宫产史;急诊CS的主要风险因素是臀位和头盆不称。在研究期间,CS比例稳定。我们发现丹麦不同医院之间风险调整后的CS存在差异。尽管应用了详尽的模型,但结果表明医院单位之间存在系统性差异,这在丹麦这样一个小而管理良好的国家是出乎意料的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7523/5829888/18be37a71a40/bmjopen-2017-019120f01.jpg

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