Manchester Thoracic Oncology Centre, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
Division of Molecular and Clinical Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Thorax. 2019 Apr;74(4):405-409. doi: 10.1136/thoraxjnl-2017-211377. Epub 2018 Feb 13.
We report baseline results of a community-based, targeted, low-dose CT (LDCT) lung cancer screening pilot in deprived areas of Manchester. Ever smokers, aged 55-74 years, were invited to 'lung health checks' (LHCs) next to local shopping centres, with immediate access to LDCT for those at high risk (6-year risk ≥1.51%, PLCO calculator). 75% of attendees (n=1893/2541) were ranked in the lowest deprivation quintile; 56% were high risk and of 1384 individuals screened, 3% (95% CI 2.3% to 4.1%) had lung cancer (80% early stage) of whom 65% had surgical resection. Taking lung cancer screening into communities, with an LHC approach, is effective and engages populations in deprived areas.
我们报告了在曼彻斯特贫困地区开展的一项基于社区的、有针对性的低剂量 CT（LDCT）肺癌筛查试点的基线结果。我们邀请了年龄在 55-74 岁之间的曾吸烟者在当地购物中心附近进行“肺部健康检查”（LHC），对于那些高风险的人（PLCO 计算器计算的 6 年风险≥1.51%）可以立即进行 LDCT 检查。有 75%的参与者（n=1893/2541）被归为最低贫困五分位数；56%为高风险人群，在筛查的 1384 人中，有 3%（95%CI 2.3%至 4.1%）患有肺癌（80%为早期），其中 65%接受了手术切除。将肺癌筛查带入社区，采用 LHC 方法，是有效的，并使贫困地区的人群参与其中。
