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超声联合细针穿刺细胞学检查用于早期乳腺癌患者腋窝淋巴结的评估

Ultrasound combined with fine needle aspiration cytology for the assessment of axillary lymph nodes in patients with early stage breast cancer.

作者信息

Zhang Fan, Zhang Jing, Meng Qing-Xin, Zhang Xin

机构信息

Department of Image Institute Department of Anatomy, Mudanjiang Medical University Department of Functional Section, The Second Affiliated Hospital of Mudanjiang Medical University, Mudanjiang, China.

出版信息

Medicine (Baltimore). 2018 Feb;97(7):e9855. doi: 10.1097/MD.0000000000009855.

Abstract

This study aimed to explore the clinical usefulness of ultrasound-guided fine needle aspiration cytology (USG-FNAC) for the evaluation of axillary lymph nodes in patients with early stage breast cancer (BC) among the Chinese Han female population.Around 124 patients with early stage BC were included in this retrospective study. All patients underwent USG-FNAC (group A). Patients with proven metastasis also underwent axillary lymph node dissection (ALND) (group B). In addition, sentinel lymph node biopsy (SLNB) was performed 2 to 5 hours prior to the surgery.The sensitivity, specificity, accuracy, and positive predictive value (PPV) of axillary ultrasound were 75.0%, 75.0%, 75.0%, and 82.6%, respectively, while for USG-FNAC, they were 80.8%, 100.0%, 88.7%, and 100.0%, respectively. Significant differences were found in specificity, accuracy, and PPV between the 2 procedures (P < .05).The results of this study demonstrated that USG-FNAC was effective for selecting patients with early stage BC using ALND or SLNB among the Chinese Han female population.

摘要

本研究旨在探讨超声引导下细针穿刺细胞学检查(USG-FNAC)在中国汉族女性人群早期乳腺癌(BC)患者腋窝淋巴结评估中的临床应用价值。本回顾性研究纳入了约124例早期BC患者。所有患者均接受了USG-FNAC(A组)。确诊有转移的患者还接受了腋窝淋巴结清扫术(ALND)(B组)。此外,在手术前2至5小时进行了前哨淋巴结活检(SLNB)。腋窝超声的敏感性、特异性、准确性和阳性预测值(PPV)分别为75.0%、75.0%、75.0%和82.6%,而USG-FNAC的相应数值分别为80.8%、100.0%、88.7%和100.0%。两种检查方法在特异性、准确性和PPV方面存在显著差异(P<0.05)。本研究结果表明,在中国汉族女性人群中,USG-FNAC对于选择接受ALND或SLNB的早期BC患者是有效的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3857/5839868/a5b0c97c6e59/medi-97-e9855-g001.jpg

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