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腹腔镜手术联合尿路重建及肠道子宫内膜异位症切除术治疗深部浸润性子宫内膜异位症

Laparoscopic surgery with urinary tract reconstruction and bowel endometriosis resection for deep infiltrating endometriosis.

作者信息

Ota Yoshiaki, Andou Masaaki, Ota Ikuko

机构信息

Kurashiki Medical Center, Kurashiki, Japan.

Kurashiki Heisei Hospital, Kurashiki, Japan.

出版信息

Asian J Endosc Surg. 2018 Feb;11(1):7-14. doi: 10.1111/ases.12464. Epub 2018 Feb 14.

DOI:10.1111/ases.12464
PMID:29444547
Abstract

Deep infiltrating endometriosis (DIE) is the most severe form of endometriosis. It causes chronic pelvic pain, severe dysmenorrhea, deep dyspareunia, dyschezia, and dysuria, markedly impairing the quality of life of women of reproductive age. A number of randomized controlled trials on surgical and medical treatments to reduce the pain associated with endometriosis have been reported, but few have focused on this in DIE. DIE causes not only pain but also functional invasion to the urinary organs and bowel, such as hydronephrosis and bowel stenosis. In addition to DIE resection, surgical treatment involves adhesion separation as well as resection and reconstruction of the urinary organs and bowel; high-level skills are required. The severity of DIE should be evaluated preoperatively as accurately as possible. Using ENZIAN in conjunction with the AFS (The revised American Fertility Society classification of endometriosis) classification makes a more detailed assessment of DIE possible. The operative procedures used for laparoscopic resection of urinary DIE and reconstruction of the urinary organs are chosen based on the type of lesion (intrinsic/extrinsic) and length of stenosis. In addition to ureteroneocystostomy, the psoas bladder hitch and Boari bladder flap procedures are applied when necessary to extend the urinary tract. Bowel resection for bowel endometriosis is classified into classic segmental resection and conservative approaches (shaving/discoid). When these procedures are employed, it is advisable to work in consultation with urologists and gastroenterologists and to inform the patients of the associated risks and outcomes. Furthermore, postoperative medication is essential because it is difficult to conduct repeated surgeries.

摘要

深部浸润型子宫内膜异位症(DIE)是子宫内膜异位症最严重的形式。它会导致慢性盆腔疼痛、严重痛经、深部性交痛、排便困难和排尿困难,显著损害育龄女性的生活质量。已有多项关于减少子宫内膜异位症相关疼痛的手术和药物治疗的随机对照试验报道,但很少有针对DIE的研究。DIE不仅会引起疼痛,还会对泌尿器官和肠道造成功能性侵犯,如肾积水和肠道狭窄。除了DIE切除术,手术治疗还包括粘连分离以及泌尿器官和肠道的切除与重建;这需要高水平的技术。应尽可能在术前准确评估DIE的严重程度。将ENZIAN与AFS(美国生殖医学学会修订的子宫内膜异位症分类)分类结合使用,可以对DIE进行更详细的评估。腹腔镜切除泌尿DIE和重建泌尿器官所采用的手术方法是根据病变类型(内在/外在)和狭窄长度来选择的。除输尿管膀胱吻合术外,必要时还可采用腰大肌膀胱固定术和波阿里膀胱瓣手术来延长尿路。肠道子宫内膜异位症的肠道切除术分为经典节段性切除术和保守方法(削除/盘状切除)。采用这些手术时,建议与泌尿科医生和胃肠科医生协商,并告知患者相关风险和结果。此外,术后药物治疗至关重要,因为重复手术难度较大。

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