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医院结局评估:大型国际管理数据库中住院时间、再入院率和死亡率之间的关系

Evaluation of hospital outcomes: the relation between length-of-stay, readmission, and mortality in a large international administrative database.

作者信息

Lingsma Hester F, Bottle Alex, Middleton Steve, Kievit Job, Steyerberg Ewout W, Marang-van de Mheen Perla J

机构信息

Department of Public Health, Erasmus Medical Centre, PO box 2040, 3000, CA, Rotterdam, The Netherlands.

Imperial College, Faculty of Medicine, School of Public Health, South Kensington Campus, London, SW7 2AZ, UK.

出版信息

BMC Health Serv Res. 2018 Feb 14;18(1):116. doi: 10.1186/s12913-018-2916-1.

Abstract

BACKGROUND

Hospital mortality, readmission and length of stay (LOS) are commonly used measures for quality of care. We aimed to disentangle the correlations between these interrelated measures and propose a new way of combining them to evaluate the quality of hospital care.

METHODS

We analyzed administrative data from the Global Comparators Project from 26 hospitals on patients discharged between 2007 and 2012. We correlated standardized and risk-adjusted hospital outcomes on mortality, readmission and long LOS. We constructed a composite measure with 5 levels, based on literature review and expert advice, from survival without readmission and normal LOS (best) to mortality (worst outcome). This composite measure was analyzed using ordinal regression, to obtain a standardized outcome measure to compare hospitals.

RESULTS

Overall, we observed a 3.1% mortality rate, 7.8% readmission rate (in survivors) and 20.8% long LOS rate among 4,327,105 admissions. Mortality and LOS were correlated at the patient and the hospital level. A patient in the upper quartile LOS had higher odds of mortality (odds ratio = 1.45, 95% confidence interval 1.43-1.47) than those in the lowest quartile. Hospitals with a high standardized mortality had higher proportions of long LOS (r = 0.79, p < 0.01). Readmission rates did not correlate with either mortality or long LOS rates. The interquartile range of the standardized ordinal composite outcome was 74-117. The composite outcome had similar or better reliability in ranking hospitals than individual outcomes.

CONCLUSIONS

Correlations between different outcome measures are complex and differ between hospital- and patient-level. The proposed composite measure combines three outcomes in an ordinal fashion for a more comprehensive and reliable view of hospital performance than its component indicators.

摘要

背景

医院死亡率、再入院率和住院时间(LOS)是常用的医疗质量衡量指标。我们旨在理清这些相互关联的指标之间的相关性,并提出一种将它们结合起来的新方法,以评估医院护理质量。

方法

我们分析了全球比较项目中26家医院在2007年至2012年期间出院患者的管理数据。我们对死亡率、再入院率和长住院时间的标准化及风险调整后的医院结局进行了相关性分析。基于文献综述和专家建议,我们构建了一个有5个等级的综合指标,从无再入院且住院时间正常(最佳)到死亡(最差结局)。使用有序回归分析这个综合指标,以获得一个标准化的结局指标来比较医院。

结果

总体而言,在4327105例入院病例中,我们观察到死亡率为3.1%,再入院率(幸存者中)为7.8%,长住院时间率为20.8%。死亡率和住院时间在患者和医院层面均存在相关性。住院时间处于上四分位数的患者比处于最低四分位数的患者死亡几率更高(优势比 = 1.45,95%置信区间1.43 - 1.47)。标准化死亡率高的医院长住院时间的比例更高(r = 0.79,p < 0.01)。再入院率与死亡率或长住院时间率均无相关性。标准化有序综合结局的四分位间距为74 - 117。综合结局在对医院进行排名时比单个结局具有相似或更好的可靠性。

结论

不同结局指标之间的相关性很复杂,在医院层面和患者层面有所不同。所提出的综合指标以有序方式结合了三个结局,比其组成指标能更全面、可靠地反映医院绩效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f80/5813333/ef24191670ca/12913_2018_2916_Fig1_HTML.jpg

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