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阿尔及利亚“乌尔德杰拉尔”母羊发生地方性鼻腺癌的首例病例报告。

First case report of enzootic nasal adenocarcinoma in "Ouled Djellal" ewe in Algeria.

作者信息

Sid Nassim, Belalmi Nour El Houda, Benhamza Louiza, Ouhida Soraya, Zebiri Mohammed Ezine, Aydoğan Ahmet, Leroux Caroline

机构信息

GSPA research Laboratory (Management of Animal Health and Productions), Institute of Veterinary Sciences, Frères Mentouri University, BP 325, route Ain El Bey, Constantine, 25100, Algeria.

Institute of Veterinary Science, Elkhroub, Frères Mentouri University, BP 325, route Ain El Bey, Constantine, 25100, Algeria.

出版信息

Open Vet J. 2018;8(1):9-12. doi: 10.4314/ovj.v8i1.3. Epub 2018 Jan 19.

DOI:10.4314/ovj.v8i1.3
PMID:29445616
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5806670/
Abstract

We report clinical and pathological features of enzootic nasal adenocarcinoma (ENA) in one sheep in Algeria. A one-year-old Ouled Djellal sheep from a large herd (~1240 animals), located in Bordj Bou Arreridj, Algeria, was clinically diagnosed by the presence of persistent seromucous nasal discharge, head shaking, muzzle licking, dyspnoea, exophthalmia and frontal protrusion. The sheep was euthanized, and the necropsy was performed. Gross examination showed soft touch, pinkish-white tumour masses in the nasal cavities with distortion of the turbinates and of the medium septum. According to clinical and pathological findings, the tumour has been defined as a low grade mixed nasal adenocarcinoma, with the presence of tubular and papillary structures. This is, to our knowledge, the first report of ENA in Algeria known to be associated with enzootic nasal tumour virus (ENTV) infection. However, such association requires confirmation by direct and/or indirect viral investigation.

摘要

我们报告了阿尔及利亚一只绵羊的地方性鼻腺癌(ENA)的临床和病理特征。一只来自阿尔及利亚博尔杰布阿雷里季一个大羊群(约1240只动物)的一岁乌尔德杰拉尔绵羊,临床上表现为持续性浆液性鼻分泌物、摇头、舔鼻、呼吸困难、眼球突出和额部突出,据此做出诊断。该绵羊实施安乐死后进行了尸检。大体检查显示鼻腔内有质地柔软、粉白色的肿瘤块,鼻甲和鼻中隔变形。根据临床和病理检查结果,该肿瘤被定义为低级别混合性鼻腺癌,存在管状和乳头状结构。据我们所知,这是阿尔及利亚首例已知与地方性鼻肿瘤病毒(ENTV)感染相关的ENA报告。然而,这种关联需要通过直接和/或间接病毒检测来确认。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5cc/5806670/f8c9f6cbad85/OpenVetJ-8-9-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5cc/5806670/bc2ea3bf92ee/OpenVetJ-8-9-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5cc/5806670/f8c9f6cbad85/OpenVetJ-8-9-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5cc/5806670/bc2ea3bf92ee/OpenVetJ-8-9-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5cc/5806670/f8c9f6cbad85/OpenVetJ-8-9-g002.jpg

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Vet Microbiol. 2015 Dec 14;181(1-2):170-7. doi: 10.1016/j.vetmic.2015.08.008. Epub 2015 Aug 12.
3
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4
Development of a SYBR Green-based real-time quantitative polymerase chain reaction assay to detect enzootic nasal tumor virus in goats.建立基于 SYBR Green 的实时荧光定量聚合酶链反应检测山羊地方性鼻肿瘤病毒方法的研究。
Can J Vet Res. 2021 Apr;85(2):145-150.
5
Enzootic nasal tumor virus type 2 envelope of goats acts as a retroviral oncogene in cell transformation.山羊地方性鼻肿瘤病毒 2 型包膜在细胞转化中充当逆转录病毒癌基因。
Virus Genes. 2021 Feb;57(1):50-59. doi: 10.1007/s11262-020-01808-7. Epub 2020 Nov 5.
6
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5
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