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过去5年不良事件与乳腺癌发病率之间的关联

The Association between Adverse Events in the Last 5 Years and the Rate of Breast Cancer.

作者信息

Rastegarimehr Babak, Zahedi Atefeh, Yavari Parvin, Lotfi Mohammad Hassan, Taheri Soodejani Moslem

机构信息

Abadan School of Medical Sciences, Abadan, Iran.

Dept. of Health and Community Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Iran J Public Health. 2018 Feb;47(2):280-285.

PMID:29445639
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5810392/
Abstract

BACKGROUND

This study was conducted in Yazd Province, Central Iran aimed to investigate the relationship between adverse events and breast cancer during 2012-2014.

METHODS

Hospital-based case-control study of 150 women with breast cancer and 150 healthy women (did not have breast cancer) was conducted. Sampling was performed in the form of accessibility. Data collection was conducted using questionnaire through interview. The collected data were entered into SPSS for statistical analysis.

RESULTS

The mean age of participants was 51.58 yr. Eight percent of cases and 1.3% of the controls had experienced the sister's death over the past 5 yr, this difference was statistically significant (=0.03). Factors such as disability due to illness, divorce, unemployment, the second marriage, addiction, ill spouse, child's problems (such as conflict, unemployment, addiction, legal troubles, illness), taking care of their own parents or their husband's parents, migration, change of habitat, loss of home, communication problems, job-relevant factors were not significantly different between the two groups (>0.05). Mean of severity of adverse events in both groups was significantly different (8.92±8.29 in the case group, 5.72±5.6 in the control group) (=0.000).

CONCLUSION

There was no significant relationship between adverse events in the last 5 yr and the risk of breast cancer. Factors such as personality and ability to cope with problems may positively influence this relationship.

摘要

背景

本研究在伊朗中部的亚兹德省开展,旨在调查2012年至2014年期间不良事件与乳腺癌之间的关系。

方法

开展了一项基于医院的病例对照研究,研究对象为150名乳腺癌女性患者和150名健康女性(无乳腺癌)。采用便利抽样法。通过访谈使用问卷进行数据收集。将收集到的数据录入SPSS进行统计分析。

结果

参与者的平均年龄为51.58岁。8%的病例组和1.3%的对照组在过去5年中经历过姐妹死亡,这一差异具有统计学意义(=0.03)。疾病导致的残疾、离婚、失业、再婚、成瘾、配偶患病、孩子的问题(如冲突、失业、成瘾、法律问题、疾病)、照顾自己的父母或丈夫的父母、移民、居住地变更、房屋丧失、沟通问题、与工作相关的因素等在两组之间没有显著差异(>0.05)。两组不良事件严重程度的平均值有显著差异(病例组为8.92±8.29,对照组为5.72±5.6)(=0.000)。

结论

过去5年中的不良事件与乳腺癌风险之间没有显著关系。人格和应对问题的能力等因素可能对这种关系产生积极影响。

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