Napolitano Lena M
Acute Care Surgery, Trauma and Surgical Critical Care, University of Michigan Health System , Ann Arbor, Michigan.
Surg Infect (Larchmt). 2018 Feb/Mar;19(2):117-125. doi: 10.1089/sur.2017.278.
Sepsis is a global healthcare issue and continues to be the leading cause of death from infection. Early recognition and diagnosis of sepsis is required to prevent the transition into septic shock, which is associated with a mortality rate of 40% or more.
New definitions for sepsis and septic shock (Third International Consensus Definitions for Sepsis and Septic Shock [Sepsis-3]) have been developed. A new screening tool for sepsis (quick Sequential Organ Failure Assessment [qSOFA]) has been proposed to predict the likelihood of poor outcome in out-of-intensive care unit (ICU) patients with clinical suspicion of sepsis. The Surviving Sepsis Campaign Guidelines were recently updated and include greater evidence-based recommendations for treatment of sepsis in attempts to reduce sepsis-associated mortality. This review discusses the new Sepsis-3 definitions and guidelines.
脓毒症是一个全球性的医疗保健问题，仍然是感染导致死亡的主要原因。需要对脓毒症进行早期识别和诊断，以防止其转变为脓毒性休克，脓毒性休克的死亡率高达40%或更高。
已经制定了脓毒症和脓毒性休克的新定义（《脓毒症和脓毒性休克第三次国际共识定义》[Sepsis-3]）。已提出一种新的脓毒症筛查工具（快速序贯器官衰竭评估[qSOFA]），以预测临床怀疑患有脓毒症的非重症监护病房（ICU）患者预后不良的可能性。《拯救脓毒症运动指南》最近进行了更新，其中包括更多基于证据的脓毒症治疗建议，旨在降低脓毒症相关死亡率。本综述讨论了新的Sepsis-3定义和指南。
