Keeley Alexander, Hine Paul, Nsutebu Emmanuel
Tropical and Infectious Disease Unit, Royal Liverpool University Hospital, Liverpool, UK.
Postgrad Med J. 2017 Oct;93(1104):626-634. doi: 10.1136/postgradmedj-2016-134519. Epub 2017 Jul 29.
Sepsis is common, often fatal and requires rapid interventions to improve outcomes. While the optimal management of sepsis in the intensive care setting is the focus of extensive research interest, the mainstay of the recognition and initial management of sepsis will occur outside the intensive care setting. Therefore, it is key that institutions and clinicians remain well informed of the current updates in sepsis management and continue to use them to deliver appropriate and timely interventions to enhance patient survival. This review discusses the latest updates in sepsis care including the new consensus definition of sepsis, the outcome of the proCESS, ProMISe and ARISE trials of early goal directed therapy (EGDT), and the most recent guidelines from the Surviving Sepsis Campaign.
脓毒症很常见，往往是致命的，需要迅速干预以改善预后。虽然重症监护环境中脓毒症的最佳管理是广泛研究兴趣的焦点，但脓毒症的识别和初始管理主要将在重症监护环境之外进行。因此，各机构和临床医生及时了解脓毒症管理的最新进展，并继续利用这些进展提供适当及时的干预措施以提高患者生存率至关重要。本综述讨论了脓毒症治疗的最新进展，包括脓毒症的新共识定义、早期目标导向治疗（EGDT）的ProCESS、ProMISe和ARISE试验结果，以及拯救脓毒症运动的最新指南。
