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美国孕妇分娩住院期间伴有自杀行为的不良产科结局。

Adverse obstetric outcomes during delivery hospitalizations complicated by suicidal behavior among US pregnant women.

作者信息

Zhong Qiu-Yue, Gelaye Bizu, Smoller Jordan W, Avillach Paul, Cai Tianxi, Williams Michelle A

机构信息

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America.

Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, United States of America.

出版信息

PLoS One. 2018 Feb 15;13(2):e0192943. doi: 10.1371/journal.pone.0192943. eCollection 2018.

Abstract

OBJECTIVE

The effects of suicidal behavior on obstetric outcomes remain dangerously unquantified. We sought to report on the risk of adverse obstetric outcomes for US women with suicidal behavior at the time of delivery.

METHODS

We performed a cross-sectional analysis of delivery hospitalizations from 2007-2012 National (Nationwide) Inpatient Sample. From the same hospitalization record, International Classification of Diseases codes were used to identify suicidal behavior and adverse obstetric outcomes. Adjusted odds ratios (aOR) and 95% confidence intervals (CI) were obtained using logistic regression.

RESULTS

Of the 23,507,597 delivery hospitalizations, 2,180 were complicated by suicidal behavior. Women with suicidal behavior were at a heightened risk for outcomes including antepartum hemorrhage (aOR = 2.34; 95% CI: 1.47-3.74), placental abruption (aOR = 2.07; 95% CI: 1.17-3.66), postpartum hemorrhage (aOR = 2.33; 95% CI: 1.61-3.37), premature delivery (aOR = 3.08; 95% CI: 2.43-3.90), stillbirth (aOR = 10.73; 95% CI: 7.41-15.56), poor fetal growth (aOR = 1.70; 95% CI: 1.10-2.62), and fetal anomalies (aOR = 3.72; 95% CI: 2.57-5.40). No significant association was observed for maternal suicidal behavior with cesarean delivery, induction of labor, premature rupture of membranes, excessive fetal growth, and fetal distress. The mean length of stay was longer for women with suicidal behavior.

CONCLUSION

During delivery hospitalization, women with suicidal behavior are at increased risk for many adverse obstetric outcomes, highlighting the importance of screening for and providing appropriate clinical care for women with suicidal behavior during pregnancy.

摘要

目的

自杀行为对产科结局的影响仍未得到危险的量化。我们试图报告美国分娩时存在自杀行为的女性出现不良产科结局的风险。

方法

我们对2007 - 2012年全国住院患者样本中的分娩住院情况进行了横断面分析。利用同一住院记录中的国际疾病分类代码来识别自杀行为和不良产科结局。采用逻辑回归获得调整后的优势比(aOR)和95%置信区间(CI)。

结果

在23507597例分娩住院病例中,2180例伴有自杀行为。存在自杀行为的女性出现以下结局的风险增加,包括产前出血(aOR = 2.34;95% CI:1.47 - 3.74)、胎盘早剥(aOR = 2.07;95% CI:1.17 - 3.66)、产后出血(aOR = 2.33;95% CI:1.61 - 3.37)、早产(aOR = 3.08;95% CI:2.43 - 3.90)、死产(aOR = 10.73;95% CI:7.41 - 15.56)、胎儿生长受限(aOR = 1.70;95% CI:1.10 - 2.62)和胎儿畸形(aOR = 3.72;95% CI:2.57 - 5.40)。未观察到产妇自杀行为与剖宫产、引产、胎膜早破、胎儿过度生长和胎儿窘迫之间存在显著关联。存在自杀行为的女性平均住院时间更长。

结论

在分娩住院期间,存在自杀行为的女性出现许多不良产科结局的风险增加,这凸显了在孕期对存在自杀行为的女性进行筛查并提供适当临床护理的重要性。

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本文引用的文献

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Suicidal ideation in pregnancy: an epidemiologic review.孕期自杀意念:一项流行病学综述。
Arch Womens Ment Health. 2016 Oct;19(5):741-51. doi: 10.1007/s00737-016-0646-0. Epub 2016 Jun 21.
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Pregnancy and suicide: towards a coherent narrative.怀孕与自杀:构建连贯的叙述
Lancet Psychiatry. 2014 Aug;1(3):168-70. doi: 10.1016/S2215-0366(14)70303-7. Epub 2014 Aug 5.
4
The neurobiology of suicide.自杀的神经生物学
Lancet Psychiatry. 2014 Jun;1(1):63-72. doi: 10.1016/S2215-0366(14)70220-2. Epub 2014 Jun 4.

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