传染性瘢痕：引发肠道炎症的扳机。

Infectious Scarring: Setting the Trigger for Intestinal Inflammation.

机构信息

Division of Gastroenterology, Department of Medicine, University of Washington, Seattle, WA, USA.

出版信息

Cell Host Microbe. 2018 Feb 14;23(2):154-156. doi: 10.1016/j.chom.2018.01.017.

DOI:10.1016/j.chom.2018.01.017

Abstract

The initiating factors that trigger inflammatory bowel disease (IBD) are poorly understood. In a recent paper, Yang et al. (2017) demonstrate that IBD-like syndrome in mice can develop as a consequence of recurrent pathogen infection. Pathogenic triggering of inflammatory disease is a re-emerging concept that has significant therapeutic implications.

摘要

引发炎症性肠病 (IBD) 的起始因素目前还不甚清楚。在最近的一篇论文中，Yang 等人（2017 年）证明，小鼠的 IBD 样综合征可能是反复病原体感染的结果。炎症性疾病的病原触发是一个新出现的概念，具有重要的治疗意义。